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[鼻腔硬结病伴颈部淋巴结受累:1例报告]

[Rhinoscleroma of the cavum with expression in cervical lymph nodes: about a case].

作者信息

Lassikri Omar, Benayad Jalila, Lachhab Omar, El Ayoubi Ali, Benbouzid Mohamed Anas, Essakalli Leila

机构信息

Service d'Oto-Rhino-Laryngologie et Chirurgie Cervico-Faciale, CHU Ibn Sina, Rabat, Maroc.

出版信息

Pan Afr Med J. 2018 Jun 12;30:116. doi: 10.11604/pamj.2018.30.116.13108. eCollection 2018.

DOI:10.11604/pamj.2018.30.116.13108
PMID:30364372
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6195248/
Abstract

Rhinoscleroma is a specific granulomatous and chronic disorder with insidious evolution. It is causes by pathogen Klebsiella rhinoscleromatis. It mainly occurs in the nasal cavities and positive diagnosis is sometimes problematic. We report the case of a 19 year old female patient presenting with rhinoscleroma considered atypical due to its rare nasopharyngeal localization and its exceptional association with cervical lymphadenopathy in the right submandibular angle region. Anatomopathological exam revealed Mikulicz's cells, thus enabling the diagnosis. The patient underwent antibiotic therapy with ciprofloxacin for 16 weeks associated with washing of nasal cavities with physiological saline solution. Patient's outcome was favorable during the 14-month follow-up period.

摘要

鼻硬结病是一种具有隐匿性发展的特殊肉芽肿性慢性疾病。它由鼻硬结克雷伯菌病原体引起。主要发生在鼻腔,有时阳性诊断存在问题。我们报告一例19岁女性患者,其鼻硬结病因其罕见的鼻咽部定位以及与右下颌角区域颈部淋巴结病的特殊关联而被认为是非典型的。解剖病理学检查发现了米库利奇细胞,从而得以确诊。患者接受了环丙沙星抗生素治疗16周,并辅以生理盐水冲洗鼻腔。在14个月的随访期内患者预后良好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d7a/6195248/c0c86cb05860/PAMJ-30-116-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d7a/6195248/acca2a641a26/PAMJ-30-116-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d7a/6195248/c0c86cb05860/PAMJ-30-116-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d7a/6195248/acca2a641a26/PAMJ-30-116-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4d7a/6195248/c0c86cb05860/PAMJ-30-116-g002.jpg

相似文献

1
[Rhinoscleroma of the cavum with expression in cervical lymph nodes: about a case].[鼻腔硬结病伴颈部淋巴结受累:1例报告]
Pan Afr Med J. 2018 Jun 12;30:116. doi: 10.11604/pamj.2018.30.116.13108. eCollection 2018.
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[Rhinoscleroma: a rare chronic infection of the nasal cavities].[鼻硬结病:一种罕见的鼻腔慢性感染]
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[Spheno-ethmoidal rhinoscleroma. Report of a case and review of the literature].[蝶筛窦鼻硬结病。1例报告并文献复习]
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A case of rhinoscleroma treated with ciprofloxacin.1例用环丙沙星治疗的鼻硬结病。
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Identification of rhinoscleroma by immunoperoxidase technique.通过免疫过氧化物酶技术鉴定鼻硬结病。
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本文引用的文献

1
Rhinoscleroma: an updated experience through the last 10 years.鼻硬结病:过去十年的最新经验
Acta Otolaryngol. 2011 Apr;131(4):440-6. doi: 10.3109/00016489.2010.539264. Epub 2011 Jan 3.
2
Klebsiella rhinoscleromatis of the membranous nasal septum.鼻中隔膜部的鼻硬结克雷伯菌。
J Laryngol Otol. 2007 Oct;121(10):998-1002. doi: 10.1017/S0022215107006421. Epub 2007 Mar 15.
3
Rhinoscleroma: a clinicopathological study from the Gulf region.鼻硬结病:来自海湾地区的临床病理研究。
Singapore Med J. 2007 Feb;48(2):148-51.
4
Rhinoscleroma: eight Peruvian cases.鼻硬结病:八例秘鲁病例。
Rev Inst Med Trop Sao Paulo. 2006 Sep-Oct;48(5):295-9. doi: 10.1590/s0036-46652006000500011.
5
Nasal rhinoscleroma in a nonendemic area: a case report.非流行地区的鼻硬结病:一例报告
J Korean Med Sci. 2003 Jun;18(3):455-8. doi: 10.3346/jkms.2003.18.3.455.
6
Upper airway obstruction due to rhinoscleroma: case report.鼻硬结病导致上气道梗阻:病例报告
J Chemother. 2001 Apr;13 Suppl 1:69-72. doi: 10.1080/1120009x.2001.11782334.
7
Laryngotracheobronchial involvement in a patient with nonendemic rhinoscleroma.非地方性鼻硬结病患者的喉气管支气管受累情况
Chest. 2000 Jun;117(6):1795-8. doi: 10.1378/chest.117.6.1795.
8
Rhinoscleroma.鼻硬结病
J Med Microbiol. 2000 May;49(5):395-396. doi: 10.1099/0022-1317-49-5-395.
9
Affection of cervical lymph nodes in rhinoscleroma.鼻硬结病中的颈部淋巴结受累
J Laryngol Otol. 1974 Mar;88(3):261-9. doi: 10.1017/s0022215100078646.