Hsiao Yu-Chao, Wang Jen-Hung, Chu Chia-Hsiang, Chang Yu-Hsun, Chen Jui-Shia, Jan Rong-Hwa, Yang Shang-Hsien, Chen Ming-Chun, Chou Wei-Chih, Chu Shao-Yin, Lai Pei-Chun, Cheng Ching-Feng, Chiu Pin-Yun, Liu Yu-Hsuan, Chang Yung-Chieh
Department of Pediatrics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Department of Medical Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Front Pediatr. 2021 Feb 12;9:599730. doi: 10.3389/fped.2021.599730. eCollection 2021.
This study aimed to investigate the contribution of high body mass index (BMI) to growth velocity among school-aged children who remained in the same BMI categories for a 6-year period. This retrospective cohort study included children who enrolled in the school year 2009 and remained in the same BMI categories during their 1st, 4th, and 7th grades (6-7, 9-10, 12-13 years of age). Annual linear growth velocity and weight gain were calculated and compared between sexes, BMI groups, and different times. Risk analysis and repeated measures analysis of variance were performed to identify the impact of BMI on growth velocity. Of the 1,637 subjects, 53.0% were male, and 2.5% and 10.9% belonged to BMI groups of overweight and obese, respectively. In students between 6 and 13 years of age, obesity was associated with higher annual weight gain and height gain. Risk analysis showed that obese subjects had higher linear growth velocity than normal BMI groups of both sexes between 6 and 9 years of age. Unexpectedly, overweight and obese girls between 9 and 13 years of age had less linear growth velocity than underweight girls at the same interval. Repeated measures analysis of variance in both sexes showed a significant statistical association between BMI and different times of growth. However, the effect was less in girls between 9 and 13 years of age. Puberty may dominate over BMI as the main contributor to high growth velocity in girls with underweight BMI emerging into pubertal age.
本研究旨在调查高体重指数（BMI）对在6年期间BMI类别保持不变的学龄儿童生长速度的影响。这项回顾性队列研究纳入了2009学年入学且在1年级、4年级和7年级（6 - 7岁、9 - 10岁、12 - 13岁）期间BMI类别保持不变的儿童。计算并比较了不同性别、BMI组以及不同时间的年度线性生长速度和体重增加情况。进行了风险分析和重复测量方差分析，以确定BMI对生长速度的影响。在1637名受试者中，53.0%为男性，分别有2.5%和10.9%属于超重和肥胖BMI组。在6至13岁的学生中，肥胖与较高的年度体重增加和身高增加相关。风险分析表明，在6至9岁之间，肥胖受试者的线性生长速度高于男女正常BMI组。出乎意料的是，9至13岁的超重和肥胖女孩在同一时期的线性生长速度低于体重过轻的女孩。男女的重复测量方差分析均显示BMI与不同生长时间之间存在显著的统计学关联。然而，在9至13岁的女孩中这种影响较小。对于进入青春期的体重过轻BMI的女孩，青春期可能比BMI更能主导高生长速度。
