den Besten C, Vansant G, Weststrate J A, Deurenberg P
Department of Human Nutrition, Agricultural University, Wageningen, The Netherlands.
Am J Clin Nutr. 1988 May;47(5):840-7. doi: 10.1093/ajcn/47.5.840.
Fifteen premenopausal obese women, seven abdominal obese (AO) and eight gluteal-femoral obese (GFO), followed an energy-reduced diet of 1000 kcal/d (4.2 MJ/d) over 8 wk. Body-fat distribution was assessed using a cutoff point of 0.80 for the waist-to-hips girth ratio. Before and after the dietary treatment resting metabolic rate (RMR) and diet-induced thermogenesis (DIT) (after a normal breakfast) were measured by indirect calorimetry. Body-weight reduction and energy intake during the diet period did not differ significantly between both groups. Before weight loss the AO group had slightly greater RMR than the GFO group. After weight loss mean RMR decreased about 10% in the AO group and about 2.5% in the GFO group. Before weight loss DIT was slightly but not significantly higher in the AO group than in the GFO group. After weight loss DIT increased significantly in the GFO group. Weight loss was generally associated with decreased blood glucose, serum triglycerides, and total serum cholesterol levels in the AO women but not in the GFO women.
15名绝经前肥胖女性，其中7名腹部肥胖（AO），8名臀股部肥胖（GFO），她们遵循了为期8周、每日能量摄入减少至1000千卡（4.2兆焦）的饮食方案。采用腰臀围比0.80的临界值评估身体脂肪分布。在饮食治疗前后，通过间接测热法测量静息代谢率（RMR）和饮食诱导产热（DIT）（正常早餐后）。两组在饮食期间的体重减轻和能量摄入没有显著差异。在体重减轻之前，AO组的RMR略高于GFO组。体重减轻后，AO组的平均RMR下降了约10%，GFO组下降了约2.5%。在体重减轻之前，AO组的DIT略高于GFO组，但差异不显著。体重减轻后，GFO组的DIT显著增加。体重减轻通常与AO组女性的血糖、血清甘油三酯和总血清胆固醇水平降低有关，但GFO组女性并非如此。
