Bochna G S, Harty R F, Harned R K, Markin R S
Internal Medicine, University of Nebraska Medical Center, Omaha.
Am J Gastroenterol. 1988 May;83(5):564-8.
We describe the case of a 45-yr-old white male with portal hypertension and presumed Laennec's cirrhosis who developed squamous cell carcinoma of the esophagus 8 months after completion of a course of endoscopic variceal sclerotherapy. The epidemiology and natural history of esophageal cancer and their relationship to our patient are analyzed. This report emphasizes that squamous cell carcinoma of the esophagus should be considered in the differential diagnosis of postsclerotherapy dysphagia. Further studies will be required to determine whether or not esophageal variceal sclerotherapy is associated coincidently or causally with the development of squamous cell carcinoma of the esophagus in patients at increased risk for this condition.
我们描述了一例45岁的白人男性病例，该患者患有门静脉高压症，推测为Laennec肝硬化，在内镜下静脉曲张硬化治疗疗程结束8个月后发生了食管鳞状细胞癌。分析了食管癌的流行病学和自然史及其与我们这位患者的关系。本报告强调，在硬化治疗后吞咽困难的鉴别诊断中应考虑食管鳞状细胞癌。需要进一步研究以确定食管静脉曲张硬化治疗与食管癌发病风险增加的患者发生食管鳞状细胞癌是否存在巧合关联或因果关系。
