Li Meng, Zhang Xi-Fang, Yusufu Mayinuer, Liu Li-Juan, Wang Shuang, Wang Jin-Da, Zhang Jing-Shang, Wang Kai-Jie, Mao Ying-Yan, Cao Kai, Chen Shu-Ying, Yao Qin-Nan, Li Jian-Jun, Wan Xiu-Hua
Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Sciences Key Laboratory, Beijing, China.
Curr Eye Res. 2021 Sep;46(9):1406-1413. doi: 10.1080/02713683.2021.1887273. Epub 2021 Mar 1.
: To investigate the prevalence and clinical characteristics of myelinated retinal nerve fibre (MRNF) in a large teleophthalmology system.: All records between January 2015 and December 2015 from Daheng Prust teleophthalmology system were reviewed by 2 ophthalmologists independently. MRNF was classified into continuous group and discontinuous group according to the relationship between MRNF patches and optic disc. The number, total area and location of MRNF patches were analysed. Concomitant ocular diseases were documented.: Out of 51469 subjects, MRNF was detected in 304 eyes of 263 subjects with a prevalence rate of 0.51 ± 7.1% per subject and 0.30 ± 5.4% per eye. Among 304 eyes with MRNF, 239 (78.6%) eyes were in continuous group and 65 (21.4%) eyes were in discontinuous group. Single MRNF patch was found in 249 (81.9%) eyes and multiple MRNF patches were found in 55 (18.1%) eyes. MRNF of small size was found in 150 (49.3%) eyes. The ratios of multiple MRNF patches and small-sized MRNF in the continuous group were significantly higher than those in the discontinuous group ( = .014 and < .001). In continuous group, the MRNF patches were located most frequently in the superior region (68.6%) of the optic disc; In discontinuous group, the MRNF patches were located most frequently in the inferotemporal region (38.5%) of the retina. Epiretinal membrane (12 eyes, 3.9%) was the most common concomitant ocular disease.: MRNF is uncommon in China. MRNF usually presents unilaterally and as a single small whitish patch that is connected with optic disc.
在大型远程眼科系统中研究有髓神经纤维（MRNF）的患病率及临床特征。
由2名眼科医生独立回顾2015年1月至2015年12月来自大恒普瑞斯特远程眼科系统的所有记录。根据MRNF斑块与视盘的关系，将MRNF分为连续组和不连续组。分析MRNF斑块的数量、总面积及位置。记录合并的眼部疾病。
在51469名受试者中，263名受试者的304只眼中检测到MRNF，患病率为每位受试者0.51±7.1%，每只眼0.30±5.4%。在304只患有MRNF的眼中，239只（78.6%）眼属于连续组，65只（21.4%）眼属于不连续组。249只（81.9%）眼中发现单个MRNF斑块，55只（18.1%）眼中发现多个MRNF斑块。150只（49.3%）眼中发现小尺寸的MRNF。连续组中多个MRNF斑块和小尺寸MRNF的比例显著高于不连续组（P = 0.014和P < 0.001）。在连续组中，MRNF斑块最常位于视盘的上方区域（68.6%）；在不连续组中，MRNF斑块最常位于视网膜的颞下区域（38.5%）。视网膜前膜（12只眼，3.9%）是最常见的合并眼部疾病。
MRNF在中国并不常见。MRNF通常单侧出现，表现为单个与视盘相连的小白色斑块。
