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关于霍乱传播的历史和当代观点:我们是否在重复过去的讨论?从霍乱中吸取的教训能否应用于 COVID-19?

Historical and contemporary views on cholera transmission: are we repeating past discussions? Can lessons learned from cholera be applied to COVID-19?

机构信息

Copenhagen Center for Disaster Research, Global Health Section, Department of Public Health, University of Copenhagen, Copenhagen, Denmark.

Department of Microbiology, University of Dhaka, Dhaka, Bangladesh.

出版信息

APMIS. 2021 Jul;129(7):421-430. doi: 10.1111/apm.13102. Epub 2021 Mar 1.

Abstract

Cholera, a devastating diarrheal disease that caused several global pandemics in the last centuries, may share some similarities with the new COVID-19. Cholera has affected many populations in history and still remains a significant burden in developing countries. The main transmission route was thought to be predominantly through contaminated drinking water. However, revisiting the historical data collected during the Copenhagen 1853 cholera outbreak allowed us to re-evaluate the role of drinking-water transmission in a city-wide outbreak and reconsider some critical transmission routes, which have been neglected since the time of John Snow. Recent empirical and cohort data from Bangladesh also strengthened the dynamic potentiality of other transmission routes (food, fomite, fish, flies) for transmitting cholera. Analyzing this particular nature of the cholera disease transmission, this paper will describe how the pattern of transmission routes are similar to COVID-19 and how the method of revisiting old data can be used for further exploration of new and known diseases.

摘要

霍乱是一种具有毁灭性的腹泻病,在上个世纪曾引发过几次全球大流行,它可能与新型冠状病毒肺炎(COVID-19)有一些相似之处。历史上,霍乱曾影响过许多人群,在发展中国家仍然是一个重大负担。其主要传播途径被认为主要是通过受污染的饮用水。然而,重新审视在 1853 年哥本哈根霍乱爆发期间收集的历史数据,使我们能够重新评估饮用水传播在全市范围内爆发中的作用,并重新考虑一些自约翰·斯诺(John Snow)时代以来被忽视的关键传播途径。最近来自孟加拉国的实证和队列数据也增强了其他传播途径(食物、接触物、鱼类、苍蝇)传播霍乱的动态潜力。分析霍乱疾病传播的这种特殊性质,本文将描述传播途径的模式如何与 COVID-19 相似,以及如何利用重新审视旧数据的方法来进一步探索新的和已知的疾病。

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