State Key Laboratory of Crop Genetics and Germplasm Enhancement, College of Agronomy, Nanjing Agricultural University, Nanjing 210095, Jiangsu, P. R. China.
State Key Laboratory of Cotton Biology, Institute of Cotton Research of Chinese Academy of Agricultural Sciences, Anyang 455000, Henan, P. R. China.
Mol Plant Microbe Interact. 2021 Jul;34(7):758-769. doi: 10.1094/MPMI-02-21-0032-R. Epub 2021 Aug 15.
Cotton Verticillium wilt (CVW) is a severe soilborne disease caused by the pathogen , and it has a great impact on cotton production. Previous studies found that the biocontrol agent CEF-082 and its metabolic filtrate could reduce the incidence of CVW; however, the underlying mechanism remains unclear. The metabolic crude extract of CEF-082 increased the sensitivity of . to stress, degraded the cell wall of . , and increased the emergence and plant height of cotton. Through separation and purification of the metabolic crude extract of CEF-082, chaetoviridin A was identified and found to be highly active against . The compound caused cell necrosis and mycelial deformation, increased the production of reactive oxygen species and nitrous oxide, and inhibited the germination of microsclerotia of , enhancing the cotton plant defense response. In addition, CEF-082 also colonized cotton plants.[Formula: see text] Copyright © 2021 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license.
棉花黄萎病（CVW）是由病原菌引起的一种严重的土传病害，对棉花生产有很大影响。先前的研究发现，生防菌 CEF-082 及其代谢滤液可以降低 CVW 的发病率；然而，其潜在机制尚不清楚。CEF-082 的代谢粗提物提高了 对胁迫的敏感性，降解了 的细胞壁，并增加了棉花的出芽和株高。通过分离和纯化 CEF-082 的代谢粗提物，鉴定出 chaetoviridin A 对 具有很高的活性。该化合物导致细胞坏死和菌丝变形，增加活性氧和一氧化二氮的产生，并抑制 的微菌核萌发，增强了棉花植物的防御反应。此外，CEF-082 还定植在棉花植株上。[公式：见文本] 版权所有 © 2021 作者。这是一篇在 CC BY-NC-ND 4.0 国际许可下发布的开放获取文章。
