Sharma Shailja, Pandey Saurabh, Kulshreshtha Sourabh, Dubey Mukesh
Faculty of Forensic Sciences, Mandsaur University, SH-31, Mhow-Neemuch By-Pass Square, Rewas-Dewda Road, Mandsaur 458001, India.
Ministry of Ayush, Ayush Bhawan, New Delhi 110023, India.
Microorganisms. 2025 Jul 11;13(7):1646. doi: 10.3390/microorganisms13071646.
is a widely distributed fungal species recognized for its ability to produce a range of secondary metabolites. This fungus plays a significant ecological role by degrading organic matter and contributing to nutrient cycling in diverse ecosystems. In recent years, has attracted considerable scientific interest due to its potential as a biocontrol agent [BCA] against a wide array of diseases in numerous plant species. While the precise mechanisms of as a BCA remain poorly understood, interference competition through antibiosis is one of the key mechanisms. Moreover, can enhance plant health by promoting nutrient availability, manipulating the rhizosphere microbiome, and inducing plant defense responses. The formulation of for agricultural applications has been reported, which can significantly improve stability and efficacy under field conditions. However, despite significant advancements in omics and molecular biology technologies, the biology of is understudied. Enhanced research into the genetics and functional genomics of could pave the way for its applications in sustainable agriculture. This review summarizes the role of as a BCA, focusing on its underlying mechanisms such as genomics and transcriptomics, and the effects of application on soil health and the rhizosphere microbiome.
是一种广泛分布的真菌物种，以其产生一系列次生代谢产物的能力而闻名。这种真菌通过降解有机物并促进不同生态系统中的养分循环，发挥着重要的生态作用。近年来，由于其作为生物防治剂（BCA）对众多植物物种的多种病害具有防治潜力，已引起了相当大的科学关注。虽然其作为生物防治剂的确切机制仍知之甚少，但通过抗生作用进行干扰竞争是关键机制之一。此外， 可以通过促进养分有效性、操纵根际微生物群和诱导植物防御反应来增强植物健康。已有关于其农业应用制剂的报道，该制剂在田间条件下可显著提高稳定性和功效。然而，尽管组学和分子生物学技术取得了重大进展，但对 的生物学研究仍不足。加强对 遗传学和功能基因组学的研究可为其在可持续农业中的应用铺平道路。本综述总结了 作为生物防治剂的作用，重点关注其潜在机制，如基因组学和转录组学，以及 应用对土壤健康和根际微生物群的影响。
