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Kidney disorders as serious adverse drug reactions of remdesivir in coronavirus disease 2019: a retrospective case-noncase study.2019冠状病毒病中作为瑞德西韦严重药物不良反应的肾脏疾病：一项回顾性病例对照研究
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Liver and kidney function in patients with Covid-19 treated with remdesivir.瑞德西韦治疗的 COVID-19 患者的肝肾功能。
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Comparative Pharmacovigilance Analysis of Approved and Repurposed Antivirals for COVID-19: Insights from EudraVigilance Data.新冠病毒已批准和重新利用的抗病毒药物的比较药物警戒分析：来自欧洲药品管理局药物警戒数据库（EudraVigilance）数据的见解
Biomedicines. 2025 Jun 5;13(6):1387. doi: 10.3390/biomedicines13061387.
2
Remdesivir Use in Pediatric Patients with Acute SARS-CoV-2 Infection Is Safe and Well Tolerated.瑞德西韦用于急性SARS-CoV-2感染儿科患者是安全且耐受性良好的。
Children (Basel). 2025 Mar 6;12(3):331. doi: 10.3390/children12030331.
3
Comprehensive analysis of adverse events associated with onasemnogene abeparvovec (Zolgensma) in spinal muscular atrophy patients: insights from FAERS database.对脊髓性肌萎缩症患者中与onasemnogene abeparvovec（Zolgensma）相关的不良事件的综合分析：来自FAERS数据库的见解
Front Pharmacol. 2025 Jan 7;15:1475884. doi: 10.3389/fphar.2024.1475884. eCollection 2024.
4
The Effects of Remdesivir and Dexamethasone on Renal Sirtuin-1 Expression and Renal Function in Male Rats.雷米迪维与地塞米松对雄性大鼠肾脏 Sirtuin-1 表达和肾功能的影响。
Appl Biochem Biotechnol. 2024 Feb;196(2):632-642. doi: 10.1007/s12010-023-04529-3. Epub 2023 May 11.
5
Crosstalk between COVID-19 Infection and Kidney Diseases: A Review on the Metabolomic Approaches.新型冠状病毒肺炎感染与肾脏疾病之间的相互作用：代谢组学方法综述
Vaccines (Basel). 2023 Feb 20;11(2):489. doi: 10.3390/vaccines11020489.
6
Effect of remdesivir on adverse kidney outcomes in hospitalized patients with COVID-19 and impaired kidney function.瑞德西韦对 COVID-19 合并肾功能受损住院患者不良肾脏结局的影响。
PLoS One. 2023 Feb 27;18(2):e0279765. doi: 10.1371/journal.pone.0279765. eCollection 2023.
7
Molecular docking and molecular dynamics study Lianhua Qingwen granules (LHQW) treats COVID-19 by inhibiting inflammatory response and regulating cell survival.分子对接和分子动力学研究连花清瘟颗粒（LHQW）通过抑制炎症反应和调节细胞存活来治疗 COVID-19。
Front Cell Infect Microbiol. 2022 Nov 24;12:1044770. doi: 10.3389/fcimb.2022.1044770. eCollection 2022.
8
Remdesivir does not affect mitochondrial DNA copy number or deletion mutation frequency in aged male rats: A short report.瑞德西韦对老年雄性大鼠线粒体 DNA 拷贝数和缺失突变频率没有影响：一份简短报告。
PLoS One. 2022 Oct 26;17(10):e0271850. doi: 10.1371/journal.pone.0271850. eCollection 2022.
9
The potential of remdesivir to affect function, metabolism and proliferation of cardiac and kidney cells in vitro.瑞德西韦在体外影响心脏和肾脏细胞功能、代谢和增殖的潜力。
Arch Toxicol. 2022 Aug;96(8):2341-2360. doi: 10.1007/s00204-022-03306-1. Epub 2022 May 17.
10
Acute Kidney Injury Associated With Remdesivir: A Comprehensive Pharmacovigilance Analysis of COVID-19 Reports in FAERS.瑞德西韦相关的急性肾损伤：对美国食品药品监督管理局不良事件报告系统中COVID-19报告的全面药物警戒分析
Front Pharmacol. 2022 Mar 25;13:692828. doi: 10.3389/fphar.2022.692828. eCollection 2022.

Kidney disorders as serious adverse drug reactions of remdesivir in coronavirus disease 2019: a retrospective case-noncase study.

作者信息

Chouchana Laurent, Preta Laure-Hélène, Tisseyre Mylène, Terrier Benjamin, Treluyer Jean-Marc, Montastruc François

机构信息

Regional Center of Pharmacovigilance, Department of Pharmacology, Cochin Hospital, AP-HP, Centre-Université de Paris, Paris, France.

Regional Center of Pharmacovigilance, Department of Pharmacology, Cochin Hospital, AP-HP, Centre-Université de Paris, Paris, France.

出版信息

Kidney Int. 2021 May;99(5):1235-1236. doi: 10.1016/j.kint.2021.02.015. Epub 2021 Feb 26.

DOI:10.1016/j.kint.2021.02.015
PMID:33647327
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7907730/
Abstract
摘要