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新型冠状病毒感染后与髓鞘少突胶质细胞糖蛋白相关的脑炎

MOG-associated encephalitis following SARS-COV-2 infection.

作者信息

Peters John, Alhasan Saleh, Vogels Chantal B F, Grubaugh Nathan D, Farhadian Shelli, Longbrake Erin E

机构信息

Department of Neurology, Yale University School of Medicine, 333 Cedar St. New Haven, CT, 06510, USA.

Department of Neurology, Yale University School of Medicine, 333 Cedar St. New Haven, CT, 06510, USA.

出版信息

Mult Scler Relat Disord. 2021 May;50:102857. doi: 10.1016/j.msard.2021.102857. Epub 2021 Feb 23.

Abstract

A variety of neurologic manifestations of COVID-19 infections have been reported. Here, we present a case of steroid-responsive MOG-antibody associated encephalitis, characterized by cognitive decline, headaches, fever, unilateral FLAIR-hyperintensities, and leptomeningeal enhancement, that occurred in the setting of recent COVID-19 infection.

摘要

已有多种关于新冠病毒感染的神经系统表现的报道。在此,我们报告一例对类固醇有反应的髓鞘少突胶质细胞糖蛋白(MOG)抗体相关脑炎病例,其特征为认知功能下降、头痛、发热、单侧液体衰减反转恢复序列(FLAIR)高信号以及软脑膜强化,该病例发生在近期新冠病毒感染的背景下。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a342/7900751/c71e5ec3ef9f/gr1_lrg.jpg

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