Department of Molecular Genetic Biotechnology, Dong-A University, Busan, South Korea.
Division of Applied Life Science (BK21), Gyeongsang National University, Jinju, South Korea.
Crit Rev Biotechnol. 2021 Sep;41(6):902-917. doi: 10.1080/07388551.2021.1892580. Epub 2021 Mar 1.
Today, sustainable chemistry is a key trend in the chemical manufacturing industry due mainly to concerns over the global environment and resource security. In sustainable chemical manufacture, the choice of a bio-based feedstock plays a pivotal pillar. In terms of feedstock utilization for producing HMF, which is a multivalent platform intermediate easily convertible to valuable chemical products; biopolymers, biofuels, and other important chemicals, seagrass biomasses can be more favorable feedstocks compared with land plant resources due primarily to easy availability and no systematic farming. Moreover, seagrass feedstocks could contribute cost-effectively and sustainably producing HMF by exploiting the beach-cast seagrasses on seagrass-prairies with no feedstock cost, indicating that seagrass biomasses could be a most promising biofeedstock source for sustainable HMF production. We afford a platform bioprocessing technology that has not been attempted before for sustainable HMF production using raw seagrass biomass. This bioprocess can be operated by simple reaction conditions using inorganic Brønsted acids (mainly HCl) and ionic liquid solvents at relatively low temperatures (120-130 °C). In addition, some bioengineering strategies for improving the growth of seagrass biomass and the quantity/quality of nonstructural carbohydrates (starch, sucrose) that can be used as the feeding substrates for HMF production are also discussed. The main aim of this review is to provide some important information about breakthrough bio/technologies conducive to cost-effective and sustainable HMF production.
如今，可持续化学已成为化学制造业的一个主要趋势，这主要是由于人们对全球环境和资源安全的关注。在可持续化学制造中，生物基原料的选择起着关键作用。在用于生产 HMF 的原料选择方面，HMF 是一种多价平台中间体，容易转化为有价值的化学产品；与陆地植物资源相比，生物聚合物、生物燃料和其他重要化学品的海草生物质作为原料更具优势，主要是因为其易于获得且无需系统种植。此外，利用海草草原上的海滩海草，可以在没有原料成本的情况下，以具有成本效益且可持续的方式生产 HMF，这表明海草生物质可以作为可持续 HMF 生产最有前途的生物原料来源。我们提供了一种以前从未尝试过的平台生物加工技术，用于使用原始海草生物质可持续生产 HMF。该生物过程可以在相对较低的温度（120-130°C）下，使用无机 Brønsted 酸（主要是 HCl）和离子液体溶剂，通过简单的反应条件进行操作。此外，还讨论了一些生物工程策略，用于提高海草生物质的生长和非结构性碳水化合物（淀粉、蔗糖）的数量/质量，这些碳水化合物可用作 HMF 生产的进料底物。本文的主要目的是提供一些关于有利于降低成本和可持续 HMF 生产的突破性生物/技术的重要信息。
