Department of Molecular Genetic Engineering, Dong-A University, Busan, South Korea.
Department of Biotechnology, Dong-A University, Busan, South Korea.
Biotechnol Adv. 2019 Dec;37(8):107422. doi: 10.1016/j.biotechadv.2019.107422. Epub 2019 Aug 6.
Unlike petrorefinery, biorefinery uses carbon-based biomaterials, such as plant feedstocks, as the major feeding input materials in chemical manufacturing. To date, petroleum-based resources have been used for the production of wide spectrums of chemical products. However, petrorefinery is currently associated with a variety of issues, i.e., concerns over adverse impacts on the environment and human society. As an alternative technology, the sustainable biorefinery is a matter of great importance in industrial chemical manufacturing due primarily to its sustainability. As carbon-based resources, plants are paramount biomaterials for biorefinery process required in sustainable chemical manufacturing. In particular, raw plant-based biorefinery is a breakthrough technology for chemical manufacturing due mainly to its sustainable benefits. Nowadays, numerous biorefinery technologies have been developed for the production of industrially valuable chemicals. HMF, a versatile platform chemical, can be produced by dehydrating hexose sugars using raw plant feedstocks such as inulin-rich, starch-rich, and lignocellulosic plants and now, it is generally recognized as a chemical feedstock for future chemical manufacturing and bioenergy production. In this review article, this emerging hybrid technology is discussed in relation to the production of HMF from raw plant feedstocks mentioned above. In addition, the plant candidates useful for biorefinery processing of raw plant feedstocks are introduced and bioengineering strategy for their genetic modification is together described to provide current knowledge on sustainable biorefinery.
与石油精炼厂不同，生物精炼厂使用基于碳的生物材料，如植物原料，作为化学制造的主要进料材料。迄今为止，石油基资源已被用于生产广泛的化学产品。然而，石油精炼厂目前与多种问题相关联，例如对环境和人类社会的不利影响的担忧。作为一种替代技术，可持续生物精炼厂在工业化学制造中非常重要，主要是因为它具有可持续性。作为碳基资源，植物是生物精炼过程中所需的主要生物材料，对于可持续的化学制造至关重要。特别是，基于原材料的植物生物精炼是化学制造的一项突破性技术，主要是因为它具有可持续的优势。如今，已经开发了许多生物精炼技术来生产工业上有价值的化学品。HMF 是一种多功能的平台化学品，可以通过用富含菊糖、富含淀粉和木质纤维素的植物等原始植物原料脱水六碳糖来生产，现在它通常被认为是未来化学制造和生物能源生产的化学原料。在这篇综述文章中，讨论了这种新兴的混合技术与从上述原始植物原料生产 HMF 的关系。此外，还介绍了可用于原始植物原料生物精炼加工的植物候选物，并一起描述了它们的遗传修饰的生物工程策略，以提供关于可持续生物精炼的当前知识。
