Centro Cardiovascular da Universidade de Lisboa (CCUL), Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal; Serviço de Cardiologia, Centro Hospitalar Barreiro Montijo (CHBM), EPE, Barreiro, Portugal.
Laboratório de Biomatemática, Instituto de Medicina Preventiva, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal.
Rev Port Cardiol (Engl Ed). 2021 Mar;40(3):205-217. doi: 10.1016/j.repc.2020.07.014. Epub 2021 Feb 27.
Infective endocarditis affects cardiac valves or devices and has a potentially uncertain prognosis. Little information is available on the epidemiology of this disease in Portugal.
A systematic review of all evidence published in the last 30 years to assess epidemiological data in patients hospitalized with infective endocarditis in Portuguese hospital centers.
Extensive search of all published evidence using Medline, Scopus, general search databases and in addition Portuguese medical journals was performed. All relevant studies in Portuguese or English that reported short- or long-term mortality were included.
Eighteen retrospective cohort studies (15 medical and three surgical series) were included with a total of 1872 patients assessed. The medical series included 1279 patients. Older males with predominant native left heart valve involvement were identified. Staphylococcus and streptococcus were the most frequent reported pathogens. Surgical intervention was performed on average in 29.8% of cases. The short-term mortality rate ranged from three to 37.2% (average 21.9%). Surgical cases involved older males with affected native left heart valves, emergent/urgent indication was dominant and short-term mortality ranged from 13.6 to 16%.
The current study provides a descriptive analysis of the published series of infective endocarditis in Portugal over the last 30 years. Therefore, it may serve as a starting point for the development and implementation of a multicentric prospective registry on infective endocarditis patients in Portugal that will allow a better and more accurate characterization of this special patient population.
感染性心内膜炎影响心脏瓣膜或装置，具有潜在的不确定预后。关于葡萄牙该疾病的流行病学信息很少。
系统回顾过去 30 年发表的所有证据，以评估葡萄牙医院中心住院治疗感染性心内膜炎患者的流行病学数据。
使用 Medline、Scopus、一般检索数据库以及葡萄牙医学期刊广泛搜索所有已发表的证据。纳入所有报告短期或长期死亡率的葡萄牙语或英语相关研究。
纳入了 18 项回顾性队列研究（15 项内科和 3 项外科系列），共评估了 1872 名患者。内科系列包括 1279 名患者。年龄较大的男性，主要为原发性左心瓣膜受累。葡萄球菌和链球菌是最常见的报道病原体。平均有 29.8%的病例进行了外科干预。短期死亡率范围为 3%至 37.2%（平均 21.9%）。外科病例涉及年龄较大的男性，原发性左心瓣膜受累，急诊/紧急指征占主导地位，短期死亡率范围为 13.6%至 16%。
本研究对过去 30 年葡萄牙发表的感染性心内膜炎系列进行了描述性分析。因此，它可以作为在葡萄牙开展和实施感染性心内膜炎患者多中心前瞻性登记的起点，从而能够更好、更准确地描述这一特殊患者群体。
