Centro Cardiovascular da Universidade de Lisboa (CCUL). Faculdade de Medicina. Universidade de Lisboa. Lisboa; Serviço de Cardiologia. Centro Hospitalar Barreiro/Montijo (CHBM). Barreiro. Portugal.
Laboratório de Biomatemática. Instituto de Saúde Ambiental. Faculdade de Medicina. Universidade de Lisboa. Lisboa. Portugal.
Acta Med Port. 2021 Dec 2;34(12):833-841. doi: 10.20344/amp.14609. Epub 2021 Mar 8.
Infective endocarditis presents a high rate of morbidity and mortality. Population-based studies addressing mortality caused by infective endocarditis in Portugal are scarce. We aimed to study deaths caused by Infective endocarditis, as well as corresponding demographics and temporal trends.
Retrospective cohort study of all patients whose main cause of death was Infective endocarditis in Portugal from 2002 to 2018. The data was obtained from the national death certificate information system.
In Portugal, 3634 people died from infective endocarditis throughout the 17-year study period - infective endocarditis specific mortality rate of 2.1 per 100 000 habitants. Of all deceased, 89% were at least 60 years old, and most were women (55%). Overall, 72% died in a healthcare institution. An annual 9% increase in the incidence death rate from Infective endocarditis was observed, with a significant upward trend during the colder months.
In Portugal, mortality by infective endocarditis increased, mainly affecting older patients and women, and which can partially be explained by factors such as ageing of the population. The management of older patients with infective endocarditis is challenging as they present a higher number of comorbidities, more valvular heart disease and valve implants, invasive medical procedures and are less likely to undergo cardiac surgery.
In addition to data on the evolution of demographics in Portugal, it is crucial to study the incidence of infective endocarditis over time to help explain these findings. The identification of factors that can be used to better model national health policies to improve clinical outcomes of infective endocarditis in Portugal is also required.
感染性心内膜炎的发病率和死亡率都很高。基于人群的研究很少涉及葡萄牙感染性心内膜炎导致的死亡率。我们旨在研究由感染性心内膜炎引起的死亡，以及相应的人口统计学和时间趋势。
这是一项回顾性队列研究，研究了 2002 年至 2018 年期间葡萄牙所有因感染性心内膜炎而死亡的患者。数据来自国家死亡证明信息系统。
在葡萄牙，17 年间共有 3634 人死于感染性心内膜炎，感染性心内膜炎的特定死亡率为每 10 万人中有 2.1 人。所有死者中，89%的人至少 60 岁，大多数是女性（55%）。总体而言，72%的人在医疗机构死亡。观察到感染性心内膜炎的发病率死亡率每年增加 9%，且在较冷的月份呈明显上升趋势。
在葡萄牙，感染性心内膜炎的死亡率上升，主要影响老年患者和女性，这部分可以通过人口老龄化等因素来解释。老年感染性心内膜炎患者的治疗具有挑战性，因为他们有更多的合并症、更多的瓣膜性心脏病和瓣膜植入物、更多的侵入性医疗程序，并且不太可能接受心脏手术。
除了有关葡萄牙人口统计学演变的数据外，研究感染性心内膜炎随时间的发生率对于帮助解释这些发现也至关重要。还需要确定可用于更好地模拟国家卫生政策的因素，以改善葡萄牙感染性心内膜炎的临床结果。
