Laboratory of Probiogenomics, Department of Chemistry, Life Sciences, and Environmental Sustainability, University of Parma, Parma, Italy.
Interdepartmental Research Centre "Microbiome Research Hub", University of Parma, Parma, Italy.
Methods Mol Biol. 2021;2278:183-193. doi: 10.1007/978-1-0716-1274-3_15.
Bifidobacteria represent highly prevalent and abundant members of the gut microbiota during mammalian infancy. In this context, bifidobacterial species have been shown to be correlated with many aspects of host health by means of direct interactions with the host and cohabiting microbes. Metagenomic sequencing of fecal DNA represents a valuable approach for taxonomic and functional profiling of bacterial populations, and has allowed us to appreciate the relevance of bifidobacterial taxa in such complex bacterial communities, especially during the first stages of life.
双歧杆菌是哺乳动物婴儿期肠道微生物群中高度普遍和丰富的成员。在这种情况下，双歧杆菌通过与宿主和共生微生物的直接相互作用，被证明与宿主健康的许多方面相关。粪便 DNA 的宏基因组测序是一种对细菌种群进行分类和功能分析的有价值的方法，它使我们能够理解双歧杆菌在这种复杂的细菌群落中的相关性，尤其是在生命的最初阶段。
