Morito Atsushi, Eto Kojiro, Matsuishi Kozue, Hamasaki Hirokazu, Morita Keisuke, Ikeshima Satoshi, Horino Kei, Shimada Shinya, Baba Hideo
Department of Surgery, Japan Community Health Care Organization Kumamoto General Hospital, 10-10 Tori-machi, Yatsushiro, Kumamoto, 866-8660, Japan.
Department of Gastroenterological Surgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Chuo-ku, Kumamoto, 860-8556, Japan.
Surg Case Rep. 2021 Mar 1;7(1):60. doi: 10.1186/s40792-021-01134-6.
Solid pseudopapillary neoplasm of the pancreas is a rare tumor in young women, metastasizing in only 5-15% of cases, and most commonly to the liver. Although treatment guidelines have not been established, surgical resection is usually performed. We report a rare case of repeat hepatectomy for liver metastases after distal pancreatectomy with solid pseudopapillary neoplasm.
The patient was a 71-year-old woman who underwent distal pancreatectomy for solid pseudopapillary neoplasm, and liver metastasis occurred 4 years after the first surgery. Partial liver resection was performed for four liver metastases, and histopathological examination revealed a diagnosis of liver metastasis from solid pseudopapillary neoplasm. However, 18 months later, liver metastases were detected again; three tumors were identified, and partial resection was performed, which has provided 18 months' recurrence-free survival.
Long-term prognosis can be expected following R0 resection for resectable liver metastasis from solid pseudopapillary neoplasm.
胰腺实性假乳头状瘤是年轻女性中罕见的肿瘤，仅5%-15%的病例会发生转移，最常见转移至肝脏。尽管尚未确立治疗指南，但通常会进行手术切除。我们报告了1例罕见的胰腺实性假乳头状瘤患者在远端胰腺切除术后因肝转移而行再次肝切除术的病例。
患者为一名71岁女性，因胰腺实性假乳头状瘤接受了远端胰腺切除术，首次手术后4年发生肝转移。对4处肝转移灶进行了部分肝切除，组织病理学检查确诊为胰腺实性假乳头状瘤肝转移。然而，18个月后再次检测到肝转移；发现3个肿瘤，并进行了部分切除，患者已获得18个月的无复发生存期。
对于可切除的胰腺实性假乳头状瘤肝转移，R0切除术后可预期获得长期预后。
