经动脉化疗栓塞治疗胰腺实性假乳头状上皮性肿瘤肝转移：一例报告。
Transarterial chemoembolization for liver metastases from solid pseudopapillary epithelial neoplasm of pancreas: A case report.
作者信息
Prasad T V, Madhusudhan K S, Srivastava Deep N, Dash Nihar R, Gupta Arun K
机构信息
TV Prasad, KS Madhusudhan, Deep N Srivastava, Arun K Gupta, Department of Radiology, All India Institute of Medical Sciences, New Delhi 110029, India.
出版信息
World J Radiol. 2015 Mar 28;7(3):61-5. doi: 10.4329/wjr.v7.i3.61.
Abstract
Solid pseudo-papillary epithelial neoplasm (SPEN) is a rare epithelial tumor of pancreas with a low malignant potential occurs most commonly in young females. We report a case of 40 years old woman presented with extensive liver metastasis from SPEN of pancreatic body for which she was operated four years ago. Due to the extensive nature of metastatic disease she was offered Transarterial chemoembolisation (TACE) using gemcitabine as chemotherapeutic agent. Short term follow up after a month of TACE with multiphase computed tomography showed > 90% resolution in the viable tumor with significant clinical improvement. TACE ensures targeted delivery of chemotherapeutic drugs in higher doses with least systemic toxicity and is more effective and safe than systemic chemotherapy. TACE with gemcitabine was found to be very effective in our patient with numerous liver metastasis.
摘要
实性假乳头状上皮性肿瘤（SPEN）是一种罕见的胰腺上皮性肿瘤，恶性潜能低，最常见于年轻女性。我们报告一例40岁女性，四年前因胰体部SPEN出现广泛肝转移而接受手术。由于转移性疾病范围广泛，她接受了以吉西他滨为化疗药物的经动脉化疗栓塞术（TACE）。TACE术后一个月的短期随访中，多期计算机断层扫描显示存活肿瘤消退>90%，临床症状显著改善。TACE可确保高剂量化疗药物的靶向递送，全身毒性最小，比全身化疗更有效、更安全。我们发现，TACE联合吉西他滨对我们这位有多处肝转移的患者非常有效。
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