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运动后线粒体损伤的机制与预防。

The mechanism and prevention of mitochondrial injury after exercise.

机构信息

Tianjin Institute of Environmental and Operational Medicine, 1 Dali Road, Heping District, Tianjin, 300050, People's Republic of China.

出版信息

J Physiol Biochem. 2021 May;77(2):215-225. doi: 10.1007/s13105-021-00802-3. Epub 2021 Mar 2.

Abstract

With the development of society, physical activity has come to be an effective means by which people pursue good health to improve the quality of life. However, with the increase of intensity and the passage of time, exercise injury has become a hazard that can no longer be ignored. It is imperative to find effective ways to inhibit or reduce the negative effects of exercise. Mitochondria are important organelles involved in exercise and play an important role in exercise injury and prevention. Studies have found that exercise preconditioning and increased mitochondrial nutrition can effectively decrease mitochondrial damage after exercise. Against this background, some of the newest developments in this important field are reviewed here. The results discussed indicate that exercise preconditioning and supplement mitochondrial nutrition need to be increased to prevent exercise-related injuries.

摘要

随着社会的发展,体力活动已成为人们追求健康、提高生活质量的有效手段。然而,随着运动强度的增加和时间的推移,运动损伤已成为一个不容忽视的危害。寻找有效方法抑制或减少运动的负面影响迫在眉睫。线粒体是与运动相关的重要细胞器,在运动损伤和预防中发挥着重要作用。研究发现,运动预处理和增加线粒体营养可以有效减少运动后的线粒体损伤。在此背景下,本文综述了该重要领域的一些最新进展。讨论的结果表明,需要增加运动预处理和补充线粒体营养来预防与运动相关的损伤。

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