支气管镜在哮喘、COPD 和肺气肿中的应用管理。
Bronchoscopic management of asthma, COPD and emphysema.
机构信息
Dept of Pulmonary Medicine, University Hospital of Reims, Reims, France.
INSERM P3Cell UMR-S1250, SFR CAP-SANTE, University of Reims Champagne Ardenne, Reims, France.
出版信息
Eur Respir Rev. 2021 Jan 13;30(159). doi: 10.1183/16000617.0029-2020. Print 2021 Mar 31.
Abstract
In recent years, many bronchoscopic techniques have been developed in chronic obstructive airway inflammatory diseases, including asthma, COPD and emphysema. The main techniques with available data from randomised controlled trials are: 1) bronchial thermoplasty in asthma; 2) valves, coils and thermal vapor ablation in emphysema; and 3) targeted lung denervation in COPD. The objectives of this article are to describe the levels of evidence for efficacy and safety, long-term follow-up results beyond 1 year, and current recommendations for clinical practice from international guidelines for each technique.
摘要
近年来，在慢性阻塞性气道炎症性疾病（包括哮喘、COPD 和肺气肿）中已经开发出许多支气管镜技术。具有随机对照试验数据的主要技术包括：1）哮喘的支气管热成形术；2）肺气肿的阀门、线圈和热蒸汽消融术；3）COPD 的靶向肺去神经支配术。本文的目的是描述每种技术的疗效和安全性的证据水平、1 年以上的长期随访结果以及国际指南对临床实践的当前建议。
相似文献
1
Bronchoscopic management of asthma, COPD and emphysema.支气管镜在哮喘、COPD 和肺气肿中的应用管理。
Eur Respir Rev. 2021 Jan 13;30(159). doi: 10.1183/16000617.0029-2020. Print 2021 Mar 31.
2
[Interventionen beim Asthma COPD].[哮喘慢性阻塞性肺疾病的干预措施]
Ther Umsch. 2019 Nov;76(6):328-336. doi: 10.1024/0040-5930/a001097.
3
Lung Volume Reduction Coils as a Novel Bronchoscopic Treatment for Emphysema.肺减容线圈作为一种治疗肺气肿的新型支气管镜治疗方法。
Methodist Debakey Cardiovasc J. 2016 Oct-Dec;12(4 Suppl):17. doi: 10.14797/mdcj-12-4s1-17.
4
Impact of bronchoscopic thermal vapor ablation on lung volume reduction in patients with emphysema: a meta-analysis.支气管镜热蒸汽消融对肺气肿患者肺减容的影响：一项荟萃分析。
BMC Pulm Med. 2023 Oct 26;23(1):405. doi: 10.1186/s12890-023-02689-w.
5
Current status of interventional therapy for pulmonary emphysema with bronchoscopy.支气管镜介入治疗肺气肿的现状。
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2022 May 28;47(5):665-672. doi: 10.11817/j.issn.1672-7347.2022.210120.
6
[Bronchoscopic treatments for COPD].[慢性阻塞性肺疾病的支气管镜治疗]
Nihon Rinsho. 2016 May;74(5):807-12.
7
Interventional pulmonology in chronic obstructive pulmonary disease.慢性阻塞性肺疾病的介入肺病学
Curr Opin Pulm Med. 2017 May;23(3):261-268. doi: 10.1097/MCP.0000000000000373.
8
Surgical and bronchoscopic pulmonary function-improving procedures in lung emphysema.肺肺气肿的手术和支气管镜肺功能改善术。
Eur Respir Rev. 2023 Dec 20;32(170). doi: 10.1183/16000617.0004-2023. Print 2023 Dec 31.
9
Novel Endoscopic Approaches to Treating Chronic Obstructive Pulmonary Disease and Emphysema.治疗慢性阻塞性肺疾病和肺气肿的新型内镜方法。
Semin Respir Crit Care Med. 2015 Aug;36(4):609-15. doi: 10.1055/s-0035-1555614. Epub 2015 Aug 3.
10
Interventional pulmonology for chronic inflammatory airway diseases.慢性炎症性气道疾病的介入肺脏病学
Chin Med J Pulm Crit Care Med. 2024 Sep 17;2(3):171-181. doi: 10.1016/j.pccm.2024.08.001. eCollection 2024 Sep.
引用本文的文献
1
Long-Term Outcomes of Interventional Bronchoscopy for Central Airway Obstruction in a Single-Center Retrospective Study: A Subgroup Analysis of Malignant and Benign Lesions.单中心回顾性研究中经支气管镜介入治疗中央气道阻塞的长期结果：恶性和良性病变的亚组分析
J Clin Med. 2025 Mar 21;14(7):2155. doi: 10.3390/jcm14072155.
2
A prediction model for risk of low oxygen saturation in patients with post-tuberculosis tracheobronchial stenosis during bronchoscopy.肺结核性支气管狭窄患者支气管镜检查中低氧饱和度风险预测模型。
Ther Adv Respir Dis. 2023 Jan-Dec;17:17534666231216573. doi: 10.1177/17534666231216573.
3
Bronchoscopic Management of COPD and Advances in Therapy.慢性阻塞性肺疾病的支气管镜管理与治疗进展
Life (Basel). 2023 Apr 18;13(4):1036. doi: 10.3390/life13041036.
本文引用的文献
1
Design for a multicenter, randomized, sham-controlled study to evaluate safety and efficacy after treatment with the Nuvaira® lung denervation system in subjects with chronic obstructive pulmonary disease (AIRFLOW-3).一项多中心、随机、假手术对照研究的设计，旨在评估 Nuvaira® 肺去神经治疗系统治疗慢性阻塞性肺疾病（AIRFLOW-3）患者的安全性和疗效。
BMC Pulm Med. 2020 Feb 13;20(1):41. doi: 10.1186/s12890-020-1058-5.
2
5-Year Survival after Endobronchial Coil Implantation: Secondary Analysis of the First Randomised Controlled Trial, RESET.支气管腔内线圈植入术后 5 年生存：RESET 首个随机对照试验的二次分析。
Respiration. 2020;99(2):154-162. doi: 10.1159/000505274. Epub 2020 Jan 22.
3
Safety and Adverse Events after Targeted Lung Denervation for Symptomatic Moderate to Severe Chronic Obstructive Pulmonary Disease (AIRFLOW). A Multicenter Randomized Controlled Clinical Trial.靶向肺去神经术治疗有症状的中重度慢性阻塞性肺疾病（AIRFLOW）的安全性和不良事件。一项多中心随机对照临床试验。
Am J Respir Crit Care Med. 2019 Dec 15;200(12):1477-1486. doi: 10.1164/rccm.201903-0624OC.
4
Long-term follow up after endoscopic valve therapy in patients with severe emphysema.重度肺气肿患者内镜下活瓣治疗后的长期随访。
Ther Adv Respir Dis. 2019 Jan-Dec;13:1753466619866101. doi: 10.1177/1753466619866101.
5
Improving Lung Function in Severe Heterogenous Emphysema with the Spiration Valve System (EMPROVE). A Multicenter, Open-Label Randomized Controlled Clinical Trial.Spiration 阀系统改善严重异质性肺气肿患者的肺功能（EMPROVE）：一项多中心、开放标签随机对照临床试验。
Am J Respir Crit Care Med. 2019 Dec 1;200(11):1354-1362. doi: 10.1164/rccm.201902-0383OC.
6
Safety and Dose Study of Targeted Lung Denervation in Moderate/Severe COPD Patients.靶向肺去神经术治疗中重度 COPD 患者的安全性和剂量研究。
Respiration. 2019;98(4):329-339. doi: 10.1159/000500463. Epub 2019 Jun 20.
7
Endoscopic Lung Volume Reduction: An Expert Panel Recommendation - Update 2019.支气管镜肺减容术：专家小组建议-2019 年更新
Respiration. 2019;97(6):548-557. doi: 10.1159/000496122. Epub 2019 Mar 5.
8
Predictors of Response to Endobronchial Coil Therapy in Patients With Advanced Emphysema.预测晚期肺气肿患者对支气管内线圈治疗反应的因素。
Chest. 2019 May;155(5):928-937. doi: 10.1016/j.chest.2019.02.012. Epub 2019 Feb 21.
9
The REACH Trial: A Randomized Controlled Trial Assessing the Safety and Effectiveness of the Spiration® Valve System in the Treatment of Severe Emphysema.REACH 试验：一项评估 Spiration® Valve 系统治疗严重肺气肿的安全性和有效性的随机对照试验。
Respiration. 2019;97(5):416-427. doi: 10.1159/000494327. Epub 2018 Dec 14.
10
Long-term safety of bilateral targeted lung denervation in patients with COPD.慢性阻塞性肺疾病患者双侧靶向肺去神经术的长期安全性
Int J Chron Obstruct Pulmon Dis. 2018 Jul 16;13:2163-2172. doi: 10.2147/COPD.S158748. eCollection 2018.
Zotero 插件