National Heart & Lung Institute, Imperial College London, London, United Kingdom.
JMIR Public Health Surveill. 2021 Apr 14;7(4):e26734. doi: 10.2196/26734.
In the face of the COVID-19 pandemic, the UK National Health Service (NHS) extended eligibility for influenza vaccination this season to approximately 32.4 million people (48.8% of the population). Knowing the intended uptake of the vaccine will inform supply and public health messaging to maximize vaccination.
The objective of this study was to measure the impact of the COVID-19 pandemic on the acceptance of influenza vaccination in the 2020-2021 season, specifically focusing on people who were previously eligible but routinely declined vaccination and newly eligible people.
Intention to receive the influenza vaccine in 2020-2021 was asked of all registrants of the largest electronic personal health record in the NHS by a web-based questionnaire on July 31, 2020. Of those who were either newly or previously eligible but had not previously received an influenza vaccination, multivariable logistic regression and network diagrams were used to examine their reasons to undergo or decline vaccination.
Among 6641 respondents, 945 (14.2%) were previously eligible but were not vaccinated; of these, 536 (56.7%) intended to receive an influenza vaccination in 2020-2021, as did 466 (68.6%) of the newly eligible respondents. Intention to receive the influenza vaccine was associated with increased age, index of multiple deprivation quintile, and considering oneself to be at high risk from COVID-19. Among those who were eligible but not intending to be vaccinated in 2020-2021, 164/543 (30.2%) gave reasons based on misinformation. Of the previously unvaccinated health care workers, 47/96 (49%) stated they would decline vaccination in 2020-2021.
In this sample, COVID-19 has increased acceptance of influenza vaccination in previously eligible but unvaccinated people and has motivated substantial uptake in newly eligible people. This study is essential for informing resource planning and the need for effective messaging campaigns to address negative misconceptions, which is also necessary for COVID-19 vaccination programs.
面对 COVID-19 大流行，英国国民保健制度（NHS）将本季流感疫苗接种的资格扩大到约 3240 万人（占人口的 48.8%）。了解疫苗的预期接种率将为供应和公共卫生信息提供依据，以最大限度地提高疫苗接种率。
本研究旨在衡量 COVID-19 大流行对 2020-2021 季节流感疫苗接种接受率的影响，特别是针对以前有资格但常规拒绝接种疫苗的人和新有资格的人。
通过在线问卷调查，于 2020 年 7 月 31 日向 NHS 最大的电子个人健康记录的所有注册者询问 2020-2021 年是否打算接种流感疫苗。对于新有资格或以前有资格但以前未接种过流感疫苗的人，使用多变量逻辑回归和网络图检查他们接种或拒绝接种的原因。
在 6641 名受访者中，有 945 名（14.2%）以前有资格但未接种疫苗；其中，536 名（56.7%）打算在 2020-2021 年接种流感疫苗，新有资格的受访者中有 466 名（68.6%）也打算接种。打算接种流感疫苗与年龄增加、多重剥夺五分位数指数以及认为自己有感染 COVID-19 的高风险有关。在 2020-2021 年不打算接种疫苗的有资格人群中，164/543（30.2%）基于错误信息给出了原因。在以前未接种疫苗的医护人员中，47/96（49%）表示他们将在 2020-2021 年拒绝接种疫苗。
在本研究样本中，COVID-19 增加了以前有资格但未接种疫苗人群对流感疫苗的接受度，并促使新有资格人群大量接种疫苗。本研究对于为资源规划提供信息以及为解决负面误解开展有效宣传活动的必要性至关重要，这对于 COVID-19 疫苗接种计划也是必要的。
