Onassis Cardiac Surgery Center, 17674 Athens, Greece.
University Research Institute of Maternal and Child Health and Precision Medicine, and UNESCO Chair on Adolescent Health Care, National and Kapodistrian University of Athens Medical School, 'Aghia Sophia' Children's Hospital, 11527 Athens, Greece.
Nutrients. 2021 Feb 26;13(3):744. doi: 10.3390/nu13030744.
Obesity represents one of the most challenging public health problems of our century. It accounts for approximately 5% of deaths worldwide, mostly owing to cardiovascular disease and its associated complications. Cardiovascular noninvasive imaging may provide early accurate information about hypertrophy and ischemia/fibrosis in obese subjects. Echocardiography and nuclear cardiology have serious limitations in obese subjects owing to poor acoustic window and attenuation artifacts, respectively. Coronary computed tomography angiography can provide information about obstructive coronary disease; however, the use of radiation is a serious disadvantage. Finally, cardiac magnetic resonance (CMR) holds the promise of an "all in one" examination by combining evaluation of function, wall motion/thickness, stress rest/perfusion, replacement and diffuse fibrosis without radiation. Future studies are required to document the cost/benefit ratio of the CMR in the evaluation of cardiovascular risk in overweight/obese children and adolescents.
肥胖症是本世纪最具挑战性的公共卫生问题之一。它导致了全球约 5%的死亡，主要归因于心血管疾病及其相关并发症。心血管无创影像学可以为肥胖患者的心肌肥厚和缺血/纤维化提供早期准确的信息。由于超声透窗不佳和衰减伪影，超声心动图和核医学在肥胖患者中存在严重的局限性。冠状动脉计算机断层血管造影可提供关于阻塞性冠状动脉疾病的信息，但辐射的使用是一个严重的缺点。最后，心脏磁共振（CMR）有望通过结合功能、壁运动/厚度、应激休息/灌注、替代和弥漫性纤维化的评估，实现“一站式”检查，而无辐射。未来的研究需要证明 CMR 在评估超重/肥胖儿童和青少年心血管风险方面的成本/效益比。
