Department of Chemistry Ugo Schiff & CSGI, University of Florence, 50019 Sesto Fiorentino (FI), Italy.
J Nanosci Nanotechnol. 2021 May 1;21(5):2778-2792. doi: 10.1166/jnn.2021.19063.
Additive manufacturing techniques (i.e., 3D printing) are rapidly becoming one of the most popular methods for the preparation of materials to be employed in many different fields, including biomedical applications. The main reason is the unique flexibility resulting from both the method itself and the variety of starting materials, requiring the combination of multidisciplinary competencies for the optimization of the process. In particular, this is the case of additive manufacturing processes based on the extrusion or jetting of nanocomposite materials, where the unique properties of nanomaterials are combined with those of a flowing matrix. This contribution focuses on the physico-chemical challenges typically faced in the 3D printing of polymeric nanocomposites and polymeric hydrogels intended for biomedical applications. The strategies to overcome those challenges are outlined, together with the characterization approaches that could help the advance of the field.
增材制造技术（即 3D 打印）正迅速成为制备材料的最受欢迎方法之一，这些材料将应用于许多不同的领域，包括生物医学应用。主要原因是该方法本身和各种起始材料所带来的独特灵活性，需要结合多学科能力来优化该过程。特别是，基于挤出或喷射纳米复合材料的增材制造工艺就是这种情况，其中纳米材料的独特性能与流动基质的性能相结合。本文重点介绍了生物医学应用中用于制备聚合物纳米复合材料和聚合物水凝胶的 3D 打印所面临的物理化学挑战。概述了克服这些挑战的策略，以及有助于该领域发展的表征方法。
