Dipartimento di Scienze Chimiche e Geologiche, Università degli Studi di Cagliari, Cittadella Universitaria, SS. 554 Bivio Sestu, 09042 Monserrato - Cagliari, Italy.
UK National Crystallography Service, School of Chemistry, Faculty of Engineering and Physical Sciences, University of Southampton, SO17 1BJ, UK.
J Nanosci Nanotechnol. 2021 May 1;21(5):2879-2891. doi: 10.1166/jnn.2021.19058.
The reactivity of thiomorpholinium -(4-methoxyphenyl)--thiomorpholin-amidodithiophosphonate ( and morpholinium -(4-methoxyphenyl)--morpholin-amidodithiophosphonate towards nickel (II) dichloride hexahydrated is presented and the hydrolysis of the relevant metal complexes investigated. The hydrolytic products (S-MorH₂)₂ [Ni(dtp)₂]²- and (O-MorH₂)₂[Ni(dtp)₂]²- were characterized by means of FT-IR, H, and P NMR and XRD and the experimented P-N cleavage investigated and elucidated by means of DFT calculations. The antimicrobial activity of the neutral nickel complex was tested against a set of Gram-positive and Gram-negative bacteria alongside with its nanodispersion in a silica matrix. The complex [Ni(S-Mor-adtp)₂] did not show antibacterial activity, whilst the nano-dispersed sample demonstrated inhibition to growth of . The nanocomposites were fully characterized by means of XRPD, TGA, SEM and dinitrogen sorption techniques.
硫代吗啉基-(4-甲氧基苯基)-硫代吗啉酰胺二硫代膦酸盐（和吗啉基-(4-甲氧基苯基)-吗啉酰胺二硫代膦酸盐）与二水合氯化镍（II）的反应性，以及相关金属配合物的水解进行了研究。水解产物（S-MorH₂）₂[Ni(dtp)₂]²-和（O-MorH₂）₂[Ni(dtp)₂]²-通过 FT-IR、H 和 P NMR 以及 XRD 进行了表征，并通过 DFT 计算研究和阐明了实验中的 P-N 裂解。中性镍配合物的抗菌活性针对一组革兰氏阳性和革兰氏阴性细菌进行了测试，同时还将其在二氧化硅基质中进行了纳米分散。配合物[Ni(S-Mor-adtp)₂]没有表现出抗菌活性，而纳米分散的样品 则表现出对 的生长抑制作用。纳米复合材料通过 XRD、TGA、SEM 和氮气吸附技术进行了全面表征。
