某些R因子对粗糙型肠杆菌科细菌对人血清敏感性的影响。
Effect of some R factors on the sensitivity of rough Enterobacteriaceae to human serum.
作者信息
Fietta A, Romero E, Siccardi A G
出版信息
Infect Immun. 1977 Nov;18(2):278-82. doi: 10.1128/iai.18.2.278-282.1977.
Abstract
Eight plasmids out of 26 tested confer partial serum resistance to Escherichia coli K-12 strains (Bhs character). Four Bhs+ plasmids were tested in a rough Salmonella typhimurium host, and three conferred partial serum resistance to this host as well. Plasmids representative of 19 different incompatibility groups were examined; the Bhs+ property was found in some (but not all) representatives of groups N, O, S, T, W, and F'lac (FI), and there was no apparent association between other plasmid markers and Bhs. It is likely that more than one mechanism can promote the Bhs+ phenotype and that Bhs genes are responsible for modifications of the surface structures involved in serum sensitivity.
摘要
在26个受试质粒中，有8个赋予大肠杆菌K - 12菌株部分血清抗性（Bhs特性）。在粗糙型鼠伤寒沙门氏菌宿主中对4个Bhs + 质粒进行了测试，其中3个也赋予该宿主部分血清抗性。检测了代表19个不同不相容群的质粒；在N、O、S、T、W和F'lac（FI）群的一些（但不是全部）代表质粒中发现了Bhs + 特性，并且其他质粒标记与Bhs之间没有明显关联。可能有不止一种机制可促进Bhs + 表型，并且Bhs基因负责对涉及血清敏感性的表面结构进行修饰。
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