增加大肠杆菌血清抗性的决定因素。
Determinants that increase the serum resistance of Escherichia coli.
作者信息
Taylor P W, Robinson M K
出版信息
Infect Immun. 1980 Jul;29(1):278-80. doi: 10.1128/iai.29.1.278-280.1980.
Abstract
The rfb locus, determining biosynthesis of O8-specific lipopolysaccharide side chains, was transferred to a rough mutant of Escherichia coli; recombinants producing a complete lipopolysaccharide were more resistant to the complement-mediated bactericidal action of human serum than the rough recipient. Inheritance of the his-linked genes for K27 antigen production did not alter the response to serum. The serum resistance of strains carrying O8 side chains, but not of strains with incomplete lipopolysaccharides, was further increased by inheritance of plasmids R1 and NR1.20
摘要
决定O8特异性脂多糖侧链生物合成的rfb基因座被转移到大肠杆菌的一个粗糙突变体中；产生完整脂多糖的重组体比粗糙受体对人血清补体介导的杀菌作用更具抗性。与组氨酸连锁的K27抗原产生基因的遗传并未改变对血清的反应。携带O8侧链的菌株的血清抗性，而非脂多糖不完整的菌株，通过R1和NR1.20质粒的遗传进一步增强。
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Genetical studies of serum resistance in Escherichia coli.大肠杆菌血清抗性的遗传学研究。
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Plasmid-mediated resistance to the bactericidal effects of normal rabbit serum.质粒介导的对正常兔血清杀菌作用的抗性。
Infect Immun. 1976 Sep;14(3):848-50. doi: 10.1128/iai.14.3.848-850.1976.
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