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刮宫术联合 Foley 球囊作为剖宫产瘢痕妊娠的一线治疗方案及其生殖结局

Suction Curettage and Foley Balloon as a First-Line Treatment Option for Caesarean Scar Pregnancy and Reproductive Outcomes.

作者信息

Aslan Melike, Yavuzkir Şeyda

机构信息

Obstetrics and Gynecology Department, Fırat University Medicine Faculty Hospital, Elazığ, Turkey.

出版信息

Int J Womens Health. 2021 Feb 23;13:239-245. doi: 10.2147/IJWH.S294520. eCollection 2021.

Abstract

BACKGROUND

Caesarean scar pregnancy (CSP) is associated with various serious pregnancy complications. This study presents the outcomes of patients treated with suction curettage and Foley balloon as the first-line treatment for CSP as well as their future outcomes in terms of successful pregnancy.

METHODS

Of the 44 patients diagnosed with CSP between January 2015 and April 2019, 42 who provided consent for the termination of pregnancy and who simultaneously underwent the transabdominal ultrasound-guided suction curettage + Foley balloon treatment were included in the study. These patients were then contacted and interviewed to collect data concerning their post-treatment number of pregnancies, number of miscarriages, number of live or dead births, mode of delivery, delivery time as well as whether any abnormal placental invasion or uterine ruptures developed.

RESULTS

Transabdominal ultrasound-guided suction curettage + Foley balloon was simultaneously performed as the first-line treatment in 42 patients with CSP. In two of these cases, wherein post-treatment level of β-hCG reached a plateau, single-dose systemic methotrexate was administered. Emergency surgical intervention, hysterectomy, massive blood transfusion and additional systemic methotrexate administration were not required. Twenty-six of 42 patients could be contacted. 18/26 were trying to conceive. 6/18 patients had secondary infertility, and 12/18 patients managed to conceive. 8/12 had caesarean delivery at full term. 1/12 was 16-week pregnant, 1/12 had tubal ectopic pregnancy and 2/12 had first-trimester abortus.

CONCLUSION

When administered as the first-line treatment for CSP, the suction curettage + Foley balloon treatment is a highly successful, cheap and easily performed minimally invasive method that requires only a short hospital stay, making it comfortable for patients. Compared with other uterine-sparing methods, it does not harm fertility and has positive effects on patients' future fertility outcomes.

摘要

背景

剖宫产瘢痕妊娠(CSP)与多种严重的妊娠并发症相关。本研究介绍了采用刮宫术联合 Foley 球囊作为 CSP 一线治疗方法的患者的治疗结果,以及她们未来成功妊娠的情况。

方法

在 2015 年 1 月至 2019 年 4 月期间诊断为 CSP 的 44 例患者中,42 例同意终止妊娠并同时接受经腹超声引导下刮宫术+Foley 球囊治疗的患者被纳入研究。随后对这些患者进行联系和访谈,收集有关其治疗后妊娠次数、流产次数、活产或死产次数、分娩方式、分娩时间以及是否发生任何异常胎盘植入或子宫破裂的数据。

结果

42 例 CSP 患者同时接受了经腹超声引导下刮宫术+Foley 球囊作为一线治疗。其中 2 例患者治疗后β-hCG 水平达到平台期,给予单剂量全身甲氨蝶呤治疗。无需紧急手术干预、子宫切除术、大量输血及额外的全身甲氨蝶呤给药。42 例患者中有 26 例能够取得联系。26 例中有 18 例尝试受孕。18 例中有 6 例继发不孕,18 例中有 12 例成功受孕。12 例中有 8 例足月剖宫产。12 例中有 1 例妊娠 16 周,12 例中有 1 例输卵管异位妊娠,12 例中有 2 例孕早期流产。

结论

刮宫术联合 Foley 球囊作为 CSP 的一线治疗方法,是一种非常成功、廉价且易于实施的微创方法,住院时间短,患者舒适度高。与其他保留子宫的方法相比,它不损害生育能力,对患者未来的生育结果有积极影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e871/7914068/4b2b94f77304/IJWH-13-239-g0001.jpg

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