Atarbashi-Moghadam Saede, Lotfi Ali, Kabiri Farnoush, Sijanivandi Soran
Department of Oral and Maxillofacial Pathology, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Department of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Iran J Otorhinolaryngol. 2021 Jan;33(114):55-59. doi: 10.22038/ijorl.2020.45912.2506.
Verruciform xanthoma (VX) is an uncommon benign lesion with the subepithelial accumulation of foamy histiocytes and superficial papillary proliferations with a bright orange hue. This lesion exhibits an oral region predilection. Its clinical differential diagnosis includes verrucous leukoplakia, verrucous carcinoma, squamous papilloma, verruca vulgaris, condyloma accuminatum, squamous cell carcinoma, and fibroepithelial polyp.
This report presents a case of VX of the ventral surface of the tongue afflicting a 33-year-old otherwise healthy male.
This case report can be valuable as a consequence of VX rarity and the similarity of its clinical features to papillary lesions. A biopsy is required for its definite diagnosis particularly when it occurs at sites with a high-risk of squamous cell carcinoma development, such as the lateral border and ventral surface of the tongue.
疣状黄色瘤（VX）是一种罕见的良性病变，其特征为上皮下有泡沫状组织细胞聚集以及具有明亮橙色色调的浅表乳头样增生。该病变好发于口腔区域。其临床鉴别诊断包括疣状白斑、疣状癌、鳞状乳头瘤、寻常疣、尖锐湿疣、鳞状细胞癌和纤维上皮性息肉。
本报告介绍了一例发生于一名33岁健康男性舌腹面的VX病例。
鉴于VX的罕见性及其临床特征与乳头状病变的相似性，本病例报告具有一定价值。特别是当VX发生于鳞状细胞癌发生风险较高的部位，如舌侧缘和舌腹面时，需要进行活检以明确诊断。
