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内镜“吸室”治疗上消化道手术后复杂的肠残端漏

Endoscopic 'suction room' to treat complex enteral stump leaks after upper gastrointestinal surgery.

作者信息

Mutignani Massimiliano, Dioscoridi Lorenzo, Venezia Ludovica, Larghi Alberto, Pugliese Francesco, Cintolo Marcello, Bonato Giulia, Forti Edoardo

机构信息

Digestive Endoscopy Unit, ASST Niguarda, Milan, Italy.

Gastroenterology Unit, Maggiore della Carità Hospital, Novara, Italy.

出版信息

Endosc Int Open. 2021 Mar;9(3):E371-E377. doi: 10.1055/a-1336-2922. Epub 2021 Feb 19.

DOI:10.1055/a-1336-2922
PMID:33655036
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7895649/
Abstract

Leaks/dehiscence of the enteral stump associated with infected peri-enteric collections after upper gastrointestinal surgery are a life-threatening adverse event, not usually endoscopically treatable. We describe a new endoscopic approach to treat complex entero-cutaneous fistulas (CECF) by creating a "suction room" through placement of multiple stents (enteral, biliary and/or pancreatic) and a large nose-enteral suction tube inside the enteral stent maintained on a continuous negative aspiration suction. Between January 2016 and December 2019, six consecutive patients referred to our unit with CECF of the enteral stump after failed redo surgeries underwent creation of a "suction room." In five patients, enteral, biliary and pancreatic stents were positioned before a nose-to-stent or nose-to-collection large 18 Fr tube placement. In one patient, a pancreatic stent was not placed. Technical and clinical success were achieved in all patients. Mean and median times of aspiration were 49 and 27 days, respectively, with a mean hospital stay of 56 days after the endoscopic procedure. Stents were successfully removed. Mean post-procedural follow-up was 17.3 months. Endoscopic creation of the "suction room" offers the unique possibility of treating complex entero-cutaneous fistulas in surgically altered sites, which are difficult to manage with standard endoscopic methods.

摘要

上消化道手术后,肠残端渗漏/裂开并伴有肠周感染性积液是一种危及生命的不良事件,通常无法通过内镜治疗。我们描述了一种新的内镜治疗方法,即通过在肠内支架内放置多个支架(肠内、胆管和/或胰管支架)和一根大口径鼻肠吸引管,并保持持续负压吸引,来创建一个“吸引室”,以治疗复杂的肠皮肤瘘(CECF)。2016年1月至2019年12月,连续6例因再次手术失败而转诊至我科的肠残端CECF患者接受了“吸引室”创建术。5例患者在放置鼻-支架或鼻-积液腔大口径18 Fr管之前先放置了肠内、胆管和胰管支架。1例患者未放置胰管支架。所有患者均取得了技术和临床成功。平均吸引时间和中位吸引时间分别为49天和27天,内镜手术后平均住院时间为56天。支架均成功取出。术后平均随访时间为17.3个月。内镜下创建“吸引室”为治疗手术改变部位的复杂肠皮肤瘘提供了独特的可能性,而这些部位用标准内镜方法难以处理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e3b/7895649/7c4131081633/10-1055-a-1336-2922-i2098ei4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e3b/7895649/b361c7d8ccf4/10-1055-a-1336-2922-i2098ei1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e3b/7895649/5ce2e0d9cb58/10-1055-a-1336-2922-i2098ei2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e3b/7895649/45f381669aca/10-1055-a-1336-2922-i2098ei3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e3b/7895649/7c4131081633/10-1055-a-1336-2922-i2098ei4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e3b/7895649/b361c7d8ccf4/10-1055-a-1336-2922-i2098ei1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e3b/7895649/5ce2e0d9cb58/10-1055-a-1336-2922-i2098ei2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e3b/7895649/45f381669aca/10-1055-a-1336-2922-i2098ei3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7e3b/7895649/7c4131081633/10-1055-a-1336-2922-i2098ei4.jpg

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Endoscopy. 2019 Dec;51(12):1146-1150. doi: 10.1055/a-0914-2855. Epub 2019 Jun 4.
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Endoscopic negative pressure therapy of the upper gastrointestinal tract.上消化道内镜负压治疗
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