Facon A, Grzybowski M, Divry M, Tsicopoulos A, Scherpereel P
Département d'Anesthésie-Réanimation Chirurgicale 2, Centre Hospitalier Universitaire, Lille.
Cah Anesthesiol. 1988 Mar-Apr;36(2):97-100.
This retrospective study concerning 96 observations from 1984 to 1987 allows to estimate the incidence of anaphylactoid reactions, the risk factors and the drugs involved in these accidents. During these three years, 96 anaphylactoid reactions due to anaesthetic drugs were collected. These anaphylactoid reactions were investigated by intradermal skin tests and in vitro by leukocyte histamine release. The drugs most often involved were the muscle relaxants and over all suxamethonium. This muscle relaxant must be reserved to strict indications.
这项关于1984年至1987年96例观察结果的回顾性研究,有助于估计类过敏反应的发生率、危险因素以及引发这些事故的药物。在这三年间,共收集到96例由麻醉药物引起的类过敏反应。通过皮内皮肤试验和体外白细胞组胺释放试验对这些类过敏反应进行了调查。最常涉及的药物是肌肉松弛剂,尤其是琥珀胆碱。这种肌肉松弛剂必须严格限于特定适应症使用。