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在使用Qfix Encompass固定系统对脑转移瘤患者进行HyperArc治疗期间患者的分次内运动。

Intra-fractional patient motion when using the Qfix Encompass immobilization system during HyperArc treatment of patients with brain metastases.

作者信息

Komiyama Riho, Ohira Shingo, Ueda Hikari, Kanayama Naoyuki, Masaoka Akira, Isono Masaru, Ueda Yoshihiro, Miyazaki Masayoshi, Teshima Teruki

机构信息

Department of Radiation Oncology, Osaka International Cancer Institute, Osaka, Japan.

Department of Medical Physics and Engineering, Osaka University Graduate School of Medicine, Suita, Japan.

出版信息

J Appl Clin Med Phys. 2021 Mar;22(3):254-260. doi: 10.1002/acm2.13143. Epub 2021 Mar 3.

Abstract

PURPOSE

This study investigated the intra-fractional motion (IM) of patients immobilized using the QFix Encompass Immobilization System during HyperArc (HA) treatment.

METHOD

HA treatment was performed on 89 patients immobilized using the Encompass. The IM during treatment (including megavoltage (MV) registration) was analyzed for six degrees of freedom including three axes of translation (anterior-posterior, superior-inferior (SI) and left-right (LR)) and three axes of rotation (pitch, roll, and yaw). Then, the no corrected IM (IM ) was retrospectively simulated (excluding MV registration) in three directions (SI, LR, and yaw). Finally, the correlation between the treatment time and the IM of the 3D vector was assessed.

RESULTS

The average IM in terms of the absolute displacement were 0.3 mm (SI), 0.3 mm (LR) and 0.2° (yaw) for Stereotactic radiosurgery (SRS), and 0.3 mm (SI), 0.2 mm (LR), and 0.2° (yaw) for stereotactic radiotherapy (SRT). The absolute maximum values of IM were <1 mm along the SI and LR axes and <1° along the yaw axis. The absolute maximum displacements for IM were >1 mm along the SI and LR axes and >1° along the yaw axis. In the correlation between the treatment time and the IM, the r-values were -0.025 and 0.027 for SRS and SRT respectively, along the axes of translation. For the axes of rotation, the r-values were 0.012 and 0.206 for SRS and SRT, respectively.

CONCLUSION

Encompass provided patient immobilization with adequate accuracy during HA treatment. The absolute maximum displacement IM was less than IM along the translational/rotational axes, and no statistically significant relationship between the treatment time and the IM was observed.

摘要

目的

本研究调查了在使用HyperArc(HA)治疗期间,采用QFix Encompass固定系统固定的患者的分次内运动(IM)情况。

方法

对89例使用Encompass固定的患者进行HA治疗。分析治疗期间的IM(包括兆伏(MV)配准)在六个自由度上的情况,包括三个平移轴(前后、上下(SI)和左右(LR))和三个旋转轴(俯仰、横滚和偏航)。然后,在三个方向(SI、LR和偏航)上回顾性模拟未校正的IM(IM )(不包括MV配准)。最后,评估治疗时间与三维向量的IM之间的相关性。

结果

立体定向放射外科(SRS)的绝对位移平均IM为0.3毫米(SI)、0.3毫米(LR)和0.2°(偏航),立体定向放射治疗(SRT)为0.3毫米(SI)、0.2毫米(LR)和0.2°(偏航)。IM的绝对最大值在SI和LR轴上<1毫米,在偏航轴上<1°。IM的绝对最大位移在SI和LR轴上>1毫米,在偏航轴上>1°。在治疗时间与IM的相关性方面,SRS和SRT在平移轴上的r值分别为-0.025和0.027。对于旋转轴,SRS和SRT的r值分别为0.012和0.206。

结论

Encompass在HA治疗期间为患者提供了足够精确的固定。绝对最大位移IM在平移/旋转轴上小于IM,且未观察到治疗时间与IM之间有统计学上的显著关系。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffae/7984469/64c057788478/ACM2-22-254-g002.jpg

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