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在 COVID-19 大流行期间为香港心力衰竭患者提供远程监测计划的成本效益:模型开发和数据分析。

Cost-effectiveness of a Telemonitoring Program for Patients With Heart Failure During the COVID-19 Pandemic in Hong Kong: Model Development and Data Analysis.

机构信息

School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China (Hong Kong).

出版信息

J Med Internet Res. 2021 Mar 3;23(3):e26516. doi: 10.2196/26516.

Abstract

BACKGROUND

The COVID-19 pandemic has caused patients to avoid seeking medical care. Provision of telemonitoring programs in addition to usual care has demonstrated improved effectiveness in managing patients with heart failure (HF).

OBJECTIVE

We aimed to examine the potential clinical and health economic outcomes of a telemonitoring program for management of patients with HF during the COVID-19 pandemic from the perspective of health care providers in Hong Kong.

METHODS

A Markov model was designed to compare the outcomes of a care under COVID-19 (CUC) group and a telemonitoring plus CUC group (telemonitoring group) in a hypothetical cohort of older patients with HF in Hong Kong. The model outcome measures were direct medical cost, quality-adjusted life-years (QALYs), and incremental cost-effectiveness ratio. Sensitivity analyses were performed to examine the model assumptions and the robustness of the base-case results.

RESULTS

In the base-case analysis, the telemonitoring group showed a higher QALY gain (1.9007) at a higher cost (US $15,888) compared to the CUC group (1.8345 QALYs at US $15,603). Adopting US $48,937/QALY (1 × the gross domestic product per capita of Hong Kong) as the willingness-to-pay threshold, telemonitoring was accepted as a highly cost-effective strategy, with an incremental cost-effective ratio of US $4292/QALY. No threshold value was identified in the deterministic sensitivity analysis. In the probabilistic sensitivity analysis, telemonitoring was accepted as cost-effective in 99.22% of 10,000 Monte Carlo simulations.

CONCLUSIONS

Compared to the current outpatient care alone under the COVID-19 pandemic, the addition of telemonitoring-mediated management to the current care for patients with HF appears to be a highly cost-effective strategy from the perspective of health care providers in Hong Kong.

摘要

背景

COVID-19 大流行导致患者避免就医。除了常规护理外,提供远程监测计划已被证明可改善心力衰竭(HF)患者的管理效果。

目的

我们旨在从香港医疗保健提供者的角度,研究在 COVID-19 大流行期间为 HF 患者管理提供远程监测计划的潜在临床和健康经济效益。

方法

设计了一个马尔可夫模型,以比较香港老年 HF 患者假设队列中在 COVID-19 下护理(CUC)组和远程监测加 CUC 组(远程监测组)的护理结果。模型结果衡量标准为直接医疗成本、质量调整生命年(QALY)和增量成本效益比。进行了敏感性分析以检查模型假设和基础案例结果的稳健性。

结果

在基础案例分析中,与 CUC 组(1.8345 QALY,成本为 15603 美元)相比,远程监测组的 QALY 增益更高(1.9007,成本为 15888 美元)。采用 48937 美元/QALY(1 倍香港人均国内生产总值)作为支付意愿阈值,远程监测被认为是一种高度符合成本效益的策略,增量成本效益比为 4292 美元/QALY。在确定性敏感性分析中未确定阈值。在概率敏感性分析中,在 10000 次蒙特卡罗模拟中,远程监测在 99.22%的情况下被认为具有成本效益。

结论

与 COVID-19 大流行下当前仅门诊护理相比,为 HF 患者提供远程监测介导的管理加现行护理似乎是香港医疗保健提供者的一种极具成本效益的策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b01/7931824/b6a28306418a/jmir_v23i3e26516_fig1.jpg

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