Department of Ophthalmology, Chungnam National University College of Medicine, Daejeon, Republic of Korea.
Department of Ophthalmology, Gyeongsang National University College of Medicine, Changwon, Republic of Korea.
Invest Ophthalmol Vis Sci. 2021 Mar 1;62(3):5. doi: 10.1167/iovs.62.3.5.
The purpose of this paper was to study the bilateral choroidal thickness (CT) symmetry and differences in healthy individuals using wide-field swept-source optical coherence tomography (SS-OCT).
All participants underwent a wide-field 16-mm 1-line scan using SS-OCT. CTs were measured at the following 12 points: 3 points at 900 µm, 1800 µm, and 2700 µm away from the nasal optic disc margin (nasal peripapillary area), 1 point at the subfovea, 6 points at 900 µm, 1800 µm, and 2700 µm away from the subfovea to the nasal and temporal areas (macular area), and 2 peripheral points at 2700 and 5400 µm from temporal point 3 (peripheral area). Bilateral CTs were measured; their correlations and differences in the corresponding regions were analyzed.
There were no statistically significant differences in CTs between the right and left eyes in all corresponding areas (all P > 0.05); they all showed significant positive correlation coefficients (r) (all P < 0.001). However, the nasal peripapillary and peripheral areas had relatively low correlation coefficients, compared to the macular areas. In addition, the bilateral CT differences were 32.60 ± 25.80 µm in the macular area, 40.67 ± 30.58 µm in the nasal peripapillary area, and 56.03 ± 45.73 µm in the peripheral area (all P < 0.001).
Overall, the CTs of each region were bilaterally symmetrical. However, the differences in CTs increased from the center to the periphery, which indicated that the anatomic variation of the nasal peripapillary and peripheral choroid was greater than that of the macula.
本研究旨在使用宽视野扫频源光学相干断层扫描（SS-OCT）研究健康个体的双侧脉络膜厚度（CT）对称性和差异。
所有参与者均接受 SS-OCT 的宽视野 16mm 1 线扫描。在以下 12 个点测量 CT：距鼻侧视盘边缘（鼻侧视盘周围区域）3 点，距离鼻侧 900µm、1800µm 和 2700µm；1 点位于黄斑中心凹下；6 点位于黄斑中心凹下至鼻侧和颞侧（黄斑区）的 900µm、1800µm 和 2700µm；2 点位于颞侧 3 点（颞侧区）2700µm 和 5400µm 处。测量双侧 CT，分析相应区域的相关性和差异。
所有相应区域的右眼和左眼 CT 均无统计学差异（均 P>0.05），均呈显著正相关系数（r）（均 P<0.001）。然而，与黄斑区相比，鼻侧视盘周围区和外周区的相关系数相对较低。此外，黄斑区双侧 CT 差值为 32.60±25.80µm，鼻侧视盘周围区为 40.67±30.58µm，外周区为 56.03±45.73µm（均 P<0.001）。
总体而言，各区域的 CT 均呈双侧对称。然而，从中心到外周，CT 差值逐渐增大，表明鼻侧视盘周围和外周脉络膜的解剖变异大于黄斑。
