全身振动疗法不能改善实验模型中的周围神经再生。
Whole-body vibration therapy does not improve the peripheral nerve regeneration in experimental model.
机构信息
Post graduation Program in Neuroscience, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul, Rio Grande do Sul, Brazil.
Comparative Histophysiology Laboratory, Department of Morphological Sciences, Institute of Basic Health Sciences, Federal University of Rio Grande do Sul, Rio Grande do Sul, Brazil.
出版信息
J Musculoskelet Neuronal Interact. 2021 Mar 1;21(1):68-78.
OBJECTIVES
Whole-body vibration (WBV) is commonly used to improve motor function, balance and functional performance, but its effects on the body are not fully understood. The main objective was to evaluate the morphometric and functional effects of WBV in an experimental nerve regeneration model.
METHODS
Wistar rats were submitted to unilateral sciatic nerve crush and treated with WBV (4-5 weeks), started at 3 or 10 days after injury. Functional performances were weekly assessed by sciatic functional index, horizontal ladder rung walking and narrow beam tests. Nerve histomorphometry analysis was assessed at the end of the protocol.
RESULTS
Injured groups, sedentary and WBV started at 3 days, had similar functional deficits. WBV, regardless of the start time, did not alter the histomorphometry parameters in the regeneration process.
CONCLUSIONS
The earlier therapy did not change the expected and natural recovery after the nerve lesion, but when the WBV starts later it seems to impair function parameter of recovery.
目的
全身振动（WBV）常用于改善运动功能、平衡和功能表现，但对其对身体的影响尚不完全了解。主要目的是评估 WBV 在实验性神经再生模型中的形态和功能效应。
方法
Wistar 大鼠进行单侧坐骨神经挤压，并在损伤后 3 或 10 天开始接受 WBV（4-5 周）治疗。每周通过坐骨神经功能指数、水平梯级行走和窄束试验评估功能表现。在方案结束时进行神经组织形态计量学分析。
结果
受伤组、静坐组和 3 天开始 WBV 组的功能缺陷相似。无论 WBV 开始时间如何，都不会改变再生过程中的组织形态计量学参数。
结论
早期治疗并没有改变神经损伤后的预期和自然恢复，但当 WBV 开始较晚时，它似乎会损害恢复的功能参数。
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