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利用蒙特卡罗方法分析电子放射治疗中的校正切伦科夫发射。

Analysis of corrected Cerenkov emission during electron radiotherapy by Monte Carlo method.

机构信息

State Key Laboratory of Transient Optics and Photonics, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an, 710119, China; School of Physics, Xi'an Jiaotong University, Xi'an, 710049, China; University of Chinese Academy of Science, Beijing, 100084, China.

State Key Laboratory of Transient Optics and Photonics, Xi'an Institute of Optics and Precision Mechanics, Chinese Academy of Sciences, Xi'an, 710119, China; Collaborative Innovation Center of Extreme Optics, Shanxi University, Taiyuan, 030006, China.

出版信息

Appl Radiat Isot. 2021 Feb;168:109481. doi: 10.1016/j.apradiso.2020.109481. Epub 2020 Oct 19.

Abstract

Cerenkov emission during electron radiotherapy had been emerging as a new dose assessment approach for clinical radiotherapy and could be imaged through a standard commercial camera. The purpose of this work aimed to study the accuracy of corrected Cerenkov emission method during electron radiotherapy by Monte Carlo (MC) method. GAMOS MC software was used to model the physics of electron therapy and calculated dose and Cerenkov photon distribution in water phantom. Compared to ionization chamber and diode measurement, MC simulated dose discrepancy was less than 1% in percentage depth dose (PDD) curves and less than. 2% in crossline profile curves, which was acceptable for clinical criterion. Compared to ionization chamber dose measurement, MC simulated Cerenkov discrepancy was less than 2% in crossline profile distribution, which was acceptable for clinical criterion. However, the Cerenkov PDD curves tended to overestimate the dose at the build-up region and underestimate the dose at the remaining attenuation region. After increasing the Cerenkov distribution depth to 2-3 mm, the discrepancy became well within 1% at the remaining attenuation region, which was acceptable for clinical criterion. Therefore, corrected Cerenkov emission could be used to assess PDD accuracy and crossline profile accuracy during electron radiotherapy.

摘要

电子放射治疗过程中的切伦科夫辐射已成为临床放射治疗中一种新的剂量评估方法,可通过标准商用相机进行成像。本工作旨在通过蒙特卡罗(MC)方法研究电子放射治疗过程中校正后的切伦科夫辐射方法的准确性。GAMOS MC 软件用于模拟电子治疗的物理过程,并计算水模中的剂量和切伦科夫光子分布。与电离室和二极管测量相比,MC 模拟剂量差异在百分深度剂量(PDD)曲线中小于 1%,在纵横比曲线中小于 0.2%,这对于临床标准是可以接受的。与电离室剂量测量相比,MC 模拟的切伦科夫差异在纵横比分布曲线中小于 2%,这对于临床标准是可以接受的。然而,切伦科夫 PDD 曲线在建成区的剂量高估,在剩余衰减区的剂量低估。当将切伦科夫分布深度增加到 2-3mm 时,剩余衰减区的差异在 1%以内,这对于临床标准是可以接受的。因此,校正后的切伦科夫发射可用于评估电子放射治疗过程中的 PDD 准确性和纵横比分布准确性。

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