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孕妇接种 COVID-19 疫苗安全吗?

Are COVID-19 vaccines safe in pregnancy?

机构信息

Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.

出版信息

Nat Rev Immunol. 2021 Apr;21(4):200-201. doi: 10.1038/s41577-021-00525-y.

DOI:10.1038/s41577-021-00525-y
PMID:33658707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7927763/
Abstract

As the COVID-19 vaccination programme starts to be rolled out, many young women are hesitant to accept the vaccine, citing concerns about fertility. Meanwhile, those offered the vaccine during pregnancy must decide whether they will accept, even though pregnant people were excluded from the clinical trials. Data on accidental pregnancies that occurred during the trials and, increasingly, outcomes in pregnant people who receive the vaccine can help these groups to make informed decisions.

摘要

随着 COVID-19 疫苗接种计划开始推出,许多年轻女性对接种疫苗犹豫不决,理由是担心生育能力。与此同时,那些在怀孕期间被提供疫苗的人必须决定是否接受,尽管孕妇被排除在临床试验之外。关于临床试验期间意外怀孕的情况的数据,以及越来越多的接受疫苗的孕妇的结果,可以帮助这些群体做出明智的决定。

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本文引用的文献

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Newborn antibodies to SARS-CoV-2 detected in cord blood after maternal vaccination - a case report.产妇接种疫苗后脐血中检测到针对 SARS-CoV-2 的新生儿抗体——病例报告。
BMC Pediatr. 2021 Mar 22;21(1):138. doi: 10.1186/s12887-021-02618-y.
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Coronavirus disease 2019 and first-trimester spontaneous abortion: a case-control study of 225 pregnant patients.新型冠状病毒肺炎与早孕期自然流产:225 例妊娠患者的病例对照研究。
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