孕妇接种新冠疫苗的考量：一项系统综述
COVID19 Vaccination Considerations for Pregnant Women: A Systematic Review.
作者信息
Ghafari Zahra, Khameneh Amin, Vahedi Leila
机构信息
Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
MD-PhD of Medical Genetics, Road Traffic Injury Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
出版信息
Iran J Nurs Midwifery Res. 2024 Jul 24;29(4):389-396. doi: 10.4103/ijnmr.ijnmr_146_22. eCollection 2024 Jul-Aug.
BACKGROUND
Following the coronavirus disease 2019 (COVID-19) pandemic, pregnant women are at a higher risk of developing severe COVID-19 disease. This study investigated whether pregnant women should get vaccinated against COVID-19 or not. Pregnant women in comparison with non-pregnant women.
MATERIALS AND METHODS
This study was a systematic review that searched the PubMed, Embase, and Scopus databases using the keywords "COVID-19" OR "SARS-CoV-2" OR "Coronavirus Disease" OR "2019-nCoV" AND "pregnancy "OR "pregnant" AND "vaccine" OR "vaccination" from January 2020 to April 2022.
RESULTS
Of the 37 selected studies, 15 (40.50%) declared positive views, 9 (24.30%) had inconclusive views, and 13 (35.20%) opposed vaccination due to a lack of adequate information.
CONCLUSIONS
Despite the discrepancies among the studies, one-third of the studies suggested that pregnant women be enrolled in clinical trials to investigate the outcomes of the COVID-19 vaccination on maternal and fetal outcomes. However, the majority of the studies recommended maternal immunization against COVID-19.
背景
在2019冠状病毒病（COVID-19）大流行之后，孕妇感染重症COVID-19疾病的风险更高。本研究调查了孕妇是否应该接种COVID-19疫苗。将孕妇与非孕妇进行比较。
材料与方法
本研究是一项系统评价，于2020年1月至2022年4月期间，使用关键词“COVID-19”或“SARS-CoV-2”或“冠状病毒病”或“2019-nCoV”以及“妊娠”或“孕妇”以及“疫苗”或“接种疫苗”检索了PubMed、Embase和Scopus数据库。
结果
在37项入选研究中，15项（40.50%）表明支持，9项（24.30%）观点不明确，13项（35.20%）因缺乏足够信息而反对接种疫苗。
结论
尽管各研究之间存在差异，但三分之一的研究建议将孕妇纳入临床试验，以研究COVID-19疫苗接种对母婴结局的影响。然而，大多数研究建议对孕妇进行COVID-19免疫接种。
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