Grover Sahil, Arya Yajur, Gaba Saurabh, Gupta Monica, Syal Arshi
Internal Medicine, Government Medical College & Hospital, Chandigarh, IND.
Cureus. 2021 Jan 28;13(1):e12958. doi: 10.7759/cureus.12958.
Tuberculosis is an established cause of pyrexia of unknown origin and can implicate practically any human organ system. Splenic involvement is common in disseminated or miliary tuberculosis following hematogenous spread, but isolated splenic involvement is a very rare phenomenon. We report the case of a 30-year-old immunocompetent female who presented with high-grade fever and dull aching pain in the left hypochondrium for three months. Laboratory data provided no diagnostic information. Abdominal ultrasonography revealed an enlarged spleen with multiple small hypoechoic lesions that were corroborated on computed tomography. No pulmonary involvement or primary focus of infection was discernible elsewhere. Splenic fine needle aspiration cytology helped clinch a histopathological diagnosis of isolated splenic tuberculosis. Administration of anti-tubercular therapy resulted in resolution of the disease and an excellent outcome in our patient.
结核病是不明原因发热的既定病因，几乎可累及人体任何器官系统。脾受累在血行播散性或粟粒性结核病中很常见，但孤立性脾受累是一种非常罕见的现象。我们报告一例30岁免疫功能正常的女性病例，她出现高热和左季肋部钝痛3个月。实验室检查未提供诊断信息。腹部超声显示脾脏肿大，有多个小的低回声病变，计算机断层扫描证实了这一点。其他部位未发现肺部受累或感染原发灶。脾脏细针穿刺细胞学检查有助于确诊孤立性脾结核的组织病理学诊断。给予抗结核治疗使疾病得到缓解，我们的患者预后良好。
