Burkman R T, Mason K J, Gold E B
Department of Gynecology and Obstetrics, School of Medicine, Johns Hopkins Medical Institutions, Baltimore, Maryland.
Contraception. 1988 Jan;37(1):21-7. doi: 10.1016/0010-7824(88)90145-x.
As part of the Women's Health Study, a case-control study conducted in nine cities in the United States, women hospitalized with an ectopic pregnancy and women hospitalized with non-gynecologic, medical or surgical diagnoses were interviewed concerning past reproductive history. There were 462 women meeting eligibility criteria in the ectopic pregnancy case group and 2326 women meeting the criteria for the control group. After adjustment for a number of possible confounders, the relative risk of ectopic pregnancy for women with a history of one induced abortion was 1.0 (95% confidence limits: 0.5 to 1.8) and was 0.9 (95% confidence limits: 0.8 to 1.1) for women with a history of two or more prior induced abortions. These results suggest that prior induced abortion does not significantly increase the risk of subsequent ectopic pregnancy.
作为美国九城市开展的一项病例对照研究——妇女健康研究的一部分，研究人员就既往生殖史对因异位妊娠住院的女性以及因非妇科、内科或外科诊断住院的女性进行了访谈。异位妊娠病例组有462名女性符合入选标准，对照组有2326名女性符合标准。在对一些可能的混杂因素进行调整后，有过一次人工流产史的女性发生异位妊娠的相对风险为1.0（95%置信区间：0.5至1.8），有过两次或更多次既往人工流产史的女性相对风险为0.9（95%置信区间：0.8至1.1）。这些结果表明，既往人工流产不会显著增加后续发生异位妊娠的风险。
