异位妊娠风险与既往人工流产史。
Risk of ectopic pregnancy and previous induced abortion.
作者信息
Tharaux-Deneux C, Bouyer J, Job-Spira N, Coste J, Spira A
机构信息
Hôpital de Bicêtre, Le Kremlin-Bicêtre, France.
出版信息
Am J Public Health. 1998 Mar;88(3):401-5. doi: 10.2105/ajph.88.3.401.
OBJECTIVES
This study investigated the role of prior history of induced abortion in subsequent ectopic pregnancies.
METHODS
Data from two French case-control studies were used to examine the effect of induced abortion on ectopic pregnancy risk. Case patients (n = 570) were women admitted for ectopic pregnancy during the study period; controls (n = 1385) were women who delivered in the same center.
RESULTS
The analysis among women with no previous ectopic pregnancy showed that, after control for the main ectopic pregnancy risk factors, prior induced abortion was associated with an increased risk of ectopic pregnancy (odds ratio [OR] = 1.5, 95% confidence interval [CI] = 1.0, 2.0); there was a significant trend between number of previous induced abortions and ectopic pregnancy risk (ORs = 1.4 for 1 previous induced abortion and 1.9 for 2 or more).
CONCLUSIONS
This study suggests that induced abortion may be a risk factor for ectopic pregnancy for women with no previous ectopic pregnancy, particularly in the case of women who have had several induced abortions.
目的
本研究调查了既往人工流产史在后续异位妊娠中的作用。
方法
来自两项法国病例对照研究的数据用于检验人工流产对异位妊娠风险的影响。病例患者（n = 570）为研究期间因异位妊娠入院的女性；对照（n = 1385）为在同一中心分娩的女性。
结果
在既往无异位妊娠的女性中进行分析发现，在控制主要异位妊娠风险因素后，既往人工流产与异位妊娠风险增加相关（比值比[OR] = 1.5，95%置信区间[CI] = 1.0，2.0）；既往人工流产次数与异位妊娠风险之间存在显著趋势（既往1次人工流产的OR为1.4，2次或更多次的OR为1.9）。
结论
本研究表明，对于既往无异位妊娠的女性，人工流产可能是异位妊娠的一个风险因素，尤其是对于有多次人工流产史的女性。
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