• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

皮肤利什曼病的治疗概述。

An overview of the treatment of cutaneous leishmaniasis.

作者信息

Garza-Tovar Talissa F, Sacriste-Hernández Marco I, Juárez-Durán Eder R, Arenas Roberto

机构信息

Dermatology Department, Hospital of Specialties 25 IMSS, Monterrey, Nuevo León.

Mycology Section, "Dr. Manuel Gea Gonzalez" General Hospital, Mexico City, Mexico.

出版信息

Fac Rev. 2020 Dec 22;9:28. doi: 10.12703/r/9-28. eCollection 2020.

DOI:10.12703/r/9-28
PMID:33659960
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7886081/
Abstract

Leishmaniasis is a neglected tropical disease caused by species of with a broad spectrum of clinical manifestations, such as cutaneous, visceral, and mucocutaneous presentations. Many drugs are used for its treatment, and a current effective one is a pentavalent antimonial, especially in developing countries. In this review, we discuss recent proposed therapies as well as their side effects.

摘要

利什曼病是一种被忽视的热带疾病,由多种利什曼原虫引起,具有广泛的临床表现,如皮肤型、内脏型和黏膜皮肤型。许多药物用于其治疗,目前一种有效的药物是五价锑剂,在发展中国家尤其如此。在本综述中,我们讨论了最近提出的治疗方法及其副作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3321/7886081/f89f07819d10/facrev-09-28-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3321/7886081/94700eb622de/facrev-09-28-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3321/7886081/f89f07819d10/facrev-09-28-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3321/7886081/94700eb622de/facrev-09-28-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3321/7886081/f89f07819d10/facrev-09-28-g002.jpg

相似文献

1
An overview of the treatment of cutaneous leishmaniasis.皮肤利什曼病的治疗概述。
Fac Rev. 2020 Dec 22;9:28. doi: 10.12703/r/9-28. eCollection 2020.
2
Application of nanotechnology in treatment of leishmaniasis: A Review.纳米技术在利什曼病治疗中的应用:综述
Acta Trop. 2017 Aug;172:86-90. doi: 10.1016/j.actatropica.2017.04.029. Epub 2017 Apr 28.
3
Pentavalent Antimonials Combined with Other Therapeutic Alternatives for the Treatment of Cutaneous and Mucocutaneous Leishmaniasis: A Systematic Review.五价锑联合其他治疗方案治疗皮肤利什曼病和黏膜皮肤利什曼病:一项系统评价
Dermatol Res Pract. 2018 Dec 24;2018:9014726. doi: 10.1155/2018/9014726. eCollection 2018.
4
Susceptibility of clinically sensitive and resistant Leishmania to pentavalent antimony in vitro.临床敏感和耐药利什曼原虫体外对五价锑的敏感性
Am J Trop Med Hyg. 1982 May;31(3 Pt 1):459-65. doi: 10.4269/ajtmh.1982.31.459.
5
Leishmaniasis: treatment updates and clinical practice guidelines review.利什曼病:治疗进展与临床实践指南综述
Curr Opin Infect Dis. 2015 Oct;28(5):426-37. doi: 10.1097/QCO.0000000000000194.
6
Leishmaniases and HIV/AIDS co-infections: review of common features and management experiences.利什曼病与艾滋病毒/艾滋病合并感染:常见特征及管理经验综述
Ethiop Med J. 2002 Apr;40 Suppl 1:37-49.
7
Species-specific antimonial sensitivity in Leishmania is driven by post-transcriptional regulation of AQP1.利什曼原虫中物种特异性的锑敏感性由水通道蛋白1(AQP1)的转录后调控驱动。
PLoS Negl Trop Dis. 2015 Feb 25;9(2):e0003500. doi: 10.1371/journal.pntd.0003500. eCollection 2015 Feb.
8
Intercalated low doses of antimonials for disseminated cutaneous leishmaniasis caused by : A successful approach in Amazonas, Brazil.低剂量插层使用锑剂治疗由……引起的播散性皮肤利什曼病:巴西亚马孙地区的一种成功方法 。 (注:原文中“caused by”后面似乎缺失了具体病因内容)
JAAD Case Rep. 2018 Nov 10;4(10):1045-1048. doi: 10.1016/j.jdcr.2018.07.014. eCollection 2018 Nov.
9
Interventions for American cutaneous and mucocutaneous leishmaniasis.美国皮肤和黏膜皮肤利什曼病的干预措施。
Cochrane Database Syst Rev. 2009 Apr 15(2):CD004834. doi: 10.1002/14651858.CD004834.pub2.
10
Clinical pattern and treatment outcome of cutaneous leishmaniasis patients in Somali region, eastern Ethiopia.埃塞俄比亚东部索马里地区皮肤利什曼病患者的临床症状及治疗结果
Skin Health Dis. 2024 Jun 30;4(5):e416. doi: 10.1002/ski2.416. eCollection 2024 Oct.

引用本文的文献

1
Experiences of Individuals with Cutaneous Leishmaniasis Receiving Intralesional Sodium Stibogluconate or Liquid Nitrogen Cryotherapy in Addis Ababa, Ethiopia-A Cross-Sectional Study.埃塞俄比亚亚的斯亚贝巴接受病灶内注射葡糖酸锑钠或液氮冷冻疗法的皮肤利什曼病患者的经历——一项横断面研究
Trop Med Infect Dis. 2025 Jul 23;10(8):203. doi: 10.3390/tropicalmed10080203.
2
Quality of Life in Pediatric Cutaneous Leishmaniasis: The Role of Lesion Type, Location, and Treatment.儿童皮肤利什曼病的生活质量:皮损类型、部位及治疗的作用
Inquiry. 2025 Jan-Dec;62:469580251344057. doi: 10.1177/00469580251344057. Epub 2025 Jun 12.
3
Progress and Prospects of Triazoles in Advanced Therapies for Parasitic Diseases.

本文引用的文献

1
Application of laser for treatment of cutaneous leishmaniasis: a review of literature.激光在皮肤利什曼病治疗中的应用:文献综述
Lasers Med Sci. 2020 Sep;35(7):1451-1457. doi: 10.1007/s10103-020-03006-1. Epub 2020 Apr 24.
2
Evaluation of in vitro antileishmanial efficacy of cyclosporin A and its non-immunosuppressive derivative, dihydrocyclosporin A.环孢素 A 及其非免疫抑制衍生物二氢环孢素 A 的体外抗利什曼原虫疗效评价。
Parasit Vectors. 2020 Feb 21;13(1):94. doi: 10.1186/s13071-020-3958-x.
3
Leishmanicidal activity of Piper marginatum Jacq. from Santarém-PA against Leishmania amazonensis.
三唑类药物在寄生虫病先进治疗方法中的进展与前景
Trop Med Infect Dis. 2025 May 20;10(5):142. doi: 10.3390/tropicalmed10050142.
4
Effectiveness of carbon dioxide cryotherapy for the treatment of cutaneous leishmaniasis: Systematic review and meta-analysis.二氧化碳冷冻疗法治疗皮肤利什曼病的有效性:系统评价与荟萃分析。
PLoS Negl Trop Dis. 2025 Jan 6;19(1):e0012741. doi: 10.1371/journal.pntd.0012741. eCollection 2025 Jan.
5
Progress in antileishmanial drugs: Mechanisms, challenges, and prospects.抗利什曼原虫药物的进展:作用机制、挑战与前景
PLoS Negl Trop Dis. 2025 Jan 3;19(1):e0012735. doi: 10.1371/journal.pntd.0012735. eCollection 2025 Jan.
6
Epoxy-a-lapachone in nanosystem: a prototype drug for leishmaniasis assessed in the binomial BALB/c - Leishmania (Leishmania) amazonensis.纳米体系中环氧化拉帕醌:用于利什曼病的原型药物,在二项式 BALB/c-利什曼原虫(利什曼原虫)亚马逊亚种中进行评估。
Mem Inst Oswaldo Cruz. 2024 Oct 28;119:e240115. doi: 10.1590/0074-02760240115. eCollection 2024.
7
Unusual Unsatisfactory Treatment in Two Patients with Imported Cutaneous Leishmaniasis.两名输入性皮肤利什曼病患者的异常不满意治疗情况。
Trop Med Infect Dis. 2024 Sep 30;9(10):227. doi: 10.3390/tropicalmed9100227.
8
Molecular Mechanisms of Drug Resistance in spp.[具体物种名称]中的耐药分子机制
Pathogens. 2024 Sep 27;13(10):835. doi: 10.3390/pathogens13100835.
9
Development of a Core Outcome Measure Instrument; "LeishCOM_LCL", for Localised Cutaneous Leishmaniasis.开发一种核心结局测量工具;“LeishCOM_LCL”,用于局限性皮肤利什曼病。
PLoS Negl Trop Dis. 2024 Aug 29;18(8):e0012393. doi: 10.1371/journal.pntd.0012393. eCollection 2024 Aug.
10
The first evaluation of the in vitro effects of silver(I)-N-heterocyclic carbene complexes on Encephalitozoon intestinalis and Leishmania major promastigotes.银(I)-N-杂环卡宾配合物对肠道原虫和利什曼原虫前鞭毛体体外作用的首次评价。
J Biol Inorg Chem. 2024 Aug;29(5):499-509. doi: 10.1007/s00775-024-02063-z. Epub 2024 Jun 26.
来自帕拉州圣塔伦的 Piper marginatum Jacq. 对亚马逊利什曼原虫的杀利什曼原虫活性。
Exp Parasitol. 2020 Mar;210:107847. doi: 10.1016/j.exppara.2020.107847. Epub 2020 Jan 28.
4
Styrylpyrone, isolated from an Amazon plant, induces cell cycle arrest and autophagy in .从亚马逊植物中分离得到的 Styrylpyrone 诱导细胞周期停滞和自噬。
Nat Prod Res. 2021 Nov;35(22):4729-4733. doi: 10.1080/14786419.2020.1715395. Epub 2020 Jan 25.
5
Antileishmanial activity of Urtica dioica extract against zoonotic cutaneous leishmaniasis.荨麻提取物对动物源皮肤利什曼病的抗利什曼原虫活性。
PLoS Negl Trop Dis. 2020 Jan 13;14(1):e0007843. doi: 10.1371/journal.pntd.0007843. eCollection 2020 Jan.
6
Antiprotozoal Activity of Turkish Essential Oil and Its Components.土耳其香精油及其成分的抗原生动物活性。
Molecules. 2019 Dec 3;24(23):4421. doi: 10.3390/molecules24234421.
7
Sertraline Delivered in Phosphatidylserine Liposomes Is Effective in an Experimental Model of Visceral Leishmaniasis.磷脂酰丝氨酸脂质体递送的舍曲林在内脏利什曼病实验模型中有效。
Front Cell Infect Microbiol. 2019 Oct 29;9:353. doi: 10.3389/fcimb.2019.00353. eCollection 2019.
8
Vaccines for leishmaniasis and the implications of their development for American tegumentary leishmaniasis.利什曼病疫苗及其开发对美国皮肤利什曼病的影响。
Hum Vaccin Immunother. 2020 Apr 2;16(4):919-930. doi: 10.1080/21645515.2019.1678998. Epub 2019 Nov 11.
9
Effectiveness of amiodarone in treatment of cutaneous leishmaniasis caused by Leishmania major.胺碘酮治疗硕大利什曼原虫引起的皮肤利什曼病的疗效。
Exp Parasitol. 2019 Oct;205:107747. doi: 10.1016/j.exppara.2019.107747. Epub 2019 Aug 20.
10
Vaccines Entered in Clinical Trials: A Review of Literature.进入临床试验的疫苗:文献综述
Int J Prev Med. 2019 Jun 7;10:95. doi: 10.4103/ijpvm.IJPVM_116_18. eCollection 2019.