鉴定对双链RNA病毒感染敏感和耐药的蓝氏贾第鞭毛虫分离株。
Identification of Giardia lamblia isolates susceptible and resistant to infection by the double-stranded RNA virus.
作者信息
Miller R L, Wang A L, Wang C C
机构信息
University of California San Francisco School of Pharmacy, Department of Pharmaceutical Chemistry 94143.
出版信息
Exp Parasitol. 1988 Jun;66(1):118-23. doi: 10.1016/0014-4894(88)90056-2.
The presence or absence of the Giardia lamblia double-stranded RNA virus (GLV) was surveyed among 38 axenic isolates of G. lamblia derived from both humans and animals. Of the 28 isolates lacking the virus, 19 could readily be infected by the virus. The remaining 9 isolates proved to be resistant to GLV infection even when the ratio between virus to parasite reached as high as 10(6) to 1. Evidence is also presented indicating that there are at least two "Portland 1" strains being used by the current scientific community, one containing the virus and the other lacking the virus.
在38株来自人和动物的蓝氏贾第鞭毛虫无菌分离株中，对蓝氏贾第鞭毛虫双链RNA病毒（GLV）的有无进行了调查。在28株未感染该病毒的分离株中，有19株能够很容易地被该病毒感染。其余9株分离株即使在病毒与寄生虫的比例高达10(6)比1时，仍被证明对GLV感染具有抗性。文中还提供了证据表明，目前科学界使用的至少有两种“波特兰1”菌株，一种含有该病毒，另一种不含该病毒。
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