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在一项针对有前驱糖尿病的南亚人群的糖尿病预防干预随机试验中,中等至剧烈体力活动的变化 - D-CLIP 试验。

Moderate-to-vigorous physical activity changes in a diabetes prevention intervention randomized trial among South Asians with prediabetes - The D-CLIP trial.

机构信息

Department of Internal Medicine, Rush Institute for Health Aging (Section of Community Epidemiology), Rush University Medical Center, Chicago, IL, USA.

Emory Global Diabetes Research Center, Hubert Department of Global Health, Emory University, Atlanta, GA, USA.

出版信息

Diabetes Res Clin Pract. 2021 Apr;174:108727. doi: 10.1016/j.diabres.2021.108727. Epub 2021 Mar 1.

DOI:10.1016/j.diabres.2021.108727
PMID:33662491
Abstract

AIMS

The Diabetes Community Lifestyle Improvement Program (D-CLIP) was a lifestyle education program to prevent diabetes in South Asians with prediabetes. This paper examines the impact of the D-CLIP intervention on moderate-to-vigorous intensity physical activity (MVPA).

METHODS

This randomized controlled trial to prevent diabetes included 573 individuals with prediabetes from Chennai, India. The intervention was designed to increase MVPA to ≥150 minutes per week. MVPA was measured by questionnaire at baseline, six, 12, 18, 24, 30 and 36 months of follow-up. Random effects models were used to examine the relationship between treatment group and odds of reporting ≥150 weekly minutes of MVPA and to examine the impact of the intervention on weekly MVPA.

RESULTS

With the exception of the proportion of respondents at baseline with a high waist circumference, selected sample characteristics did not differ at baseline between the intervention and control groups. The intervention significantly (p < 0.05) increased the proportion of respondents who reported ≥150 weekly minutes of MVPA by 28.5%, 13.6% and 14.0% at six, 12 and 18 months respectively. Mean minutes of weekly MVPA significantly (p < 0.05) increased by an additional 56.7, 34.3, 23.6 and 24.3 minutes/week at six, 12, 18, and 24 months, respectively.

CONCLUSION

The D-CLIP intervention significantly increased MVPA at six, 12 and 18 months of follow-up. Interventions to prevent diabetes in South Asians with prediabetes can significantly increase MVPA in this population.

摘要

目的

糖尿病社区生活方式改善计划(D-CLIP)是一项生活方式教育计划,旨在预防有前驱糖尿病的南亚人群发生糖尿病。本文研究了 D-CLIP 干预对中高强度体力活动(MVPA)的影响。

方法

这项预防糖尿病的随机对照试验纳入了来自印度钦奈的 573 名前驱糖尿病患者。干预旨在将 MVPA 增加到每周≥150 分钟。MVPA 通过基线、6、12、18、24、30 和 36 个月随访的问卷进行测量。采用随机效应模型检验治疗组与报告每周≥150 分钟 MVPA 的几率之间的关系,并检验干预对每周 MVPA 的影响。

结果

除了基线时高腰围比例的受访者比例外,干预组和对照组在基线时的选定样本特征没有差异。干预组在 6、12 和 18 个月时,分别有 28.5%、13.6%和 14.0%的受访者报告每周≥150 分钟的 MVPA,比例显著增加(p<0.05)。每周 MVPA 的平均分钟数分别显著增加(p<0.05)56.7、34.3、23.6 和 24.3 分钟/周。

结论

D-CLIP 干预在 6、12 和 18 个月的随访中显著增加了 MVPA。预防有前驱糖尿病的南亚人群发生糖尿病的干预措施可以显著增加该人群的 MVPA。

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