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“抽脂旅游”出问题:输血传播的巨细胞病毒疾病

'Lipo-tourism' gone wrong: blood transfusion-transmitted cytomegalovirus disease.

作者信息

Brahier Mark, Neuda Rhanika, Davis William, Poon Rita

机构信息

Georgetown University School of Medicine, Washington, DC, USA

Department of Internal Medicine, Georgetown University Medical Center, Washington, DC, USA.

出版信息

BMJ Case Rep. 2021 Mar 4;14(3):e236892. doi: 10.1136/bcr-2020-236892.

DOI:10.1136/bcr-2020-236892
PMID:33664022
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7934768/
Abstract

Medical tourism is the pursuit of more affordable surgeries; however, this comes at the risk of suboptimal standards and potential for life-threatening complications. In this case, we describe the diagnostic challenge of cytomegalovirus (CMV) pneumonia in a 40-year-old woman who experienced wound dehiscence and subsequent blood transfusion-transmitted CMV as complications of liposuction in the Dominican Republic. We explore the role of histopathology in the diagnosis of disseminated CMV, discuss the underlying aetiology of CMV pneumonia in this patient and weigh the risks and benefits of initiating antiviral therapy in an immunocompetent patient with CMV disease.

摘要

医疗旅游是为了寻求更经济实惠的手术;然而,这伴随着标准欠佳以及出现危及生命并发症的风险。在此病例中,我们描述了一名40岁女性巨细胞病毒(CMV)肺炎的诊断难题,该患者在多米尼加共和国接受抽脂手术后出现伤口裂开,随后因输血感染了CMV。我们探讨了组织病理学在播散性CMV诊断中的作用,讨论了该患者CMV肺炎的潜在病因,并权衡了对一名患有CMV疾病的免疫功能正常患者启动抗病毒治疗的风险和益处。

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BMJ Case Rep. 2021 Mar 4;14(3):e236892. doi: 10.1136/bcr-2020-236892.
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本文引用的文献

1
The use of CMVIg rescue therapy in cardiothoracic transplantation: A single-center experience over 6 years (2011-2017).CMVIg 挽救性治疗在心胸器官移植中的应用:6 年(2011-2017)单中心经验。
Clin Transplant. 2019 Aug;33(8):e13655. doi: 10.1111/ctr.13655. Epub 2019 Jul 20.
2
Cytomegalovirus infection in immunocompetent adults: Is observation still the best strategy?免疫功能正常的成年人巨细胞病毒感染:观察仍是最佳策略吗?
IDCases. 2018 Aug 28;14:e00442. doi: 10.1016/j.idcr.2018.e00442. eCollection 2018.
3
The Third International Consensus Guidelines on the Management of Cytomegalovirus in Solid-organ Transplantation.《实体器官移植中巨细胞病毒管理的第三次国际共识指南》。
Transplantation. 2018 Jun;102(6):900-931. doi: 10.1097/TP.0000000000002191.
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Definitions of Cytomegalovirus Infection and Disease in Transplant Patients for Use in Clinical Trials.用于临床试验的移植患者巨细胞病毒感染和疾病的定义。
Clin Infect Dis. 2017 Jan 1;64(1):87-91. doi: 10.1093/cid/ciw668. Epub 2016 Sep 28.
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Cytomegalovirus pneumonia in immunocompetent host: case report and literature review.免疫功能正常宿主巨细胞病毒肺炎:病例报告及文献复习。
J Clin Virol. 2012 Dec;55(4):356-9. doi: 10.1016/j.jcv.2012.08.010. Epub 2012 Sep 10.
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Overview of the diagnosis of cytomegalovirus infection.巨细胞病毒感染的诊断概述。
Infect Disord Drug Targets. 2011 Oct;11(5):466-74. doi: 10.2174/187152611797636703.
7
CMV in critically ill patients: pathogen or bystander?巨细胞病毒在危重症患者中的作用:病原体还是旁观者?
Rev Med Virol. 2010 Nov;20(6):372-9. doi: 10.1002/rmv.664.
8
Outbreak of Mycobacterium abscessus wound infections among "lipotourists" from the United States who underwent abdominoplasty in the Dominican Republic.在多米尼加共和国接受腹部整形手术的美国“吸脂游客”中爆发脓肿分枝杆菌伤口感染。
Clin Infect Dis. 2008 Apr 15;46(8):1181-8. doi: 10.1086/529191.
9
Severe cytomegalovirus infection in apparently immunocompetent patients: a systematic review.免疫功能正常患者的严重巨细胞病毒感染:一项系统评价
Virol J. 2008 Mar 27;5:47. doi: 10.1186/1743-422X-5-47.
10
The complications of 'cosmetic tourism' - an avoidable burden on the NHS.“美容旅游”的并发症——英国国家医疗服务体系可避免的负担。
J Plast Reconstr Aesthet Surg. 2007;60(9):1075-7. doi: 10.1016/j.bjps.2007.03.030. Epub 2007 May 7.