Hattrup S J, Amadio P C, Sim F H, Lombardi R M
Department of Orthopedics, Mayo Clinic, Rochester, MN.
Foot Ankle. 1988 Apr;8(5):243-7. doi: 10.1177/107110078800800503.
In a review of the Mayo Clinic files, 17 biopsy-proven cases of metastatic tumors of the foot and ankle were found; 4 additional cases were considered to have metastatic disease on the basis of clinical and radiographic evidence but no histological confirmation was available. Lung, kidney, and colon were the most common sites of the primary tumors. The patients survived as long as 28 months after discovery of the metastasis. Treatment consisted of individualized combinations of orthotics, surgery, and radiotherapy to maintain mobility. In 9 of these 17 cases, no primary lesion was identified at the time the metastasis was diagnosed. Metastatic tumors of the foot present special problems in diagnosis and management.
在对梅奥诊所档案的回顾中,发现了17例经活检证实的足踝部转移性肿瘤病例;另有4例根据临床和影像学证据被认为患有转移性疾病,但未获得组织学确诊。肺、肾和结肠是原发性肿瘤最常见的部位。患者在转移灶发现后存活长达28个月。治疗包括使用矫形器、手术和放疗的个体化组合以维持活动能力。在这17例病例中的9例中,在诊断转移灶时未发现原发性病变。足部转移性肿瘤在诊断和管理方面存在特殊问题。