Majeed Abdul, Rehman Muhammad, Hussain Iltaf, Imran Imran, Saleem Muhammad Usman, Saeed Hamid, Hashmi Furqan K, Akbar Muqarrab, Abrar Muhammad Asad, Ramzan Basit, Chaudhry Muhammad Omer, Islam Muhammad, Nisar Naveed, Rasool Muhammad Fawad
Department of Pharmacy Practice, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Department of Pharmacology, Faculty of Pharmacy, Bahauddin Zakariya University, Multan, 60800, Pakistan.
Patient Prefer Adherence. 2021 Feb 26;15:475-481. doi: 10.2147/PPA.S295012. eCollection 2021.
The current study was conducted to assess the factors contributing to treatment adherence and its impact on the quality of life (QoL) in type 2 diabetes mellitus (T2DM) patients.
A cross-sectional study was conducted between January 2020 to March 2020 among T2DM patients. The data was collected from T2DM out-patient clinics. The participants were recruited by using a simple random sampling method. To assess the association of demographics with the level of adherence, binary logistics regression analysis was applied. Moreover, the Mann-Whitney -test was used to evaluate the impact of adherence on QoL.
A total of 384 patients participated in this study. Amongst them, 60.2% were male and 39.8% were female. Low adherence was seen in illiterate patients and patients older than 40 years. The results showed that good QoL in T2DM patients was significantly associated with treatment adherence (p= 0.004).
The finding of the current study showed that the non-adherence prevailed in illiterate strata of the study population and the medication adherence significantly affects the QoL in T2DM patients. These findings suggest that health regulatory agencies should focus on implementing disease-education interventions for improving the adherence to medications in patients with long-term conditions.
进行本研究以评估2型糖尿病(T2DM)患者治疗依从性的影响因素及其对生活质量(QoL)的影响。
于2020年1月至2020年3月对T2DM患者进行了一项横断面研究。数据收集自T2DM门诊。采用简单随机抽样方法招募参与者。为评估人口统计学与依从性水平之间的关联,应用了二元逻辑回归分析。此外,使用曼-惠特尼检验来评估依从性对生活质量的影响。
共有384名患者参与了本研究。其中,60.2%为男性,39.8%为女性。文盲患者和40岁以上患者的依从性较低。结果显示,T2DM患者的良好生活质量与治疗依从性显著相关(p = 0.004)。
本研究结果表明,在研究人群的文盲阶层中不依从情况普遍存在,药物依从性显著影响T2DM患者的生活质量。这些发现表明,卫生监管机构应专注于实施疾病教育干预措施,以提高长期疾病患者的药物依从性。