Desai Nagaraj, Unni Govindan, Agarwala Rajeev, Salagre Santosh, Godbole Sanjay, Dengra Ashish, Abhyankar Mahesh V, Revankar Santosh
Namana Medical Center. Bangalore, Karnataka, India.
Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India.
Integr Blood Press Control. 2021 Feb 26;14:31-41. doi: 10.2147/IBPC.S272548. eCollection 2021.
To analyze the risk factors and comorbidities among the young Indian adults with hypertension.
This was a retrospective, multicentric real-world study which included patients diagnosed with and receiving treatment for hypertension. Data were collected from the medical records of clinics/hospitals across 623 study sites in India. Patients of either sex and aged 18-45 years were included. Demographic details (age, sex, anthropometric measurement), medical and family history, sedentary lifestyle, smoking status and alcohol consumption data were extracted. Descriptive and comparative analysis (Mann-Whitney and chi-squared test) was done.
Out of 15,006 young patients diagnosed with hypertension (men=63.6%), 65.7% belonged to the age group of >35-45 years. The median body mass index was 27.0 kg/m. Patients diagnosed with only hypertension were 29.1% while other predominant comorbidities with hypertension were diabetes mellitus (42.4%) and dyslipidemia (7.8%). Hypertension with diabetes mellitus were prevalent in the age group of >35-45 years (43.8%). More than half of the patients with hypertension (n=7656) had a sedentary lifestyle. Overall, 35.6%, 47.3%, and 56.7% of the patients were alcoholic, smokers (present and former), and had a family history of hypertension, respectively.
The results showed that among the young population, hypertension was common in the age group of >35-45 years and diabetes mellitus and dyslipidemia were common comorbidities. Family history, sedentary lifestyle, smoking, alcohol consumption, and body mass index may also contribute to hypertension.
分析印度年轻成人高血压患者的危险因素及合并症。
这是一项回顾性、多中心的真实世界研究，纳入了已诊断并接受高血压治疗的患者。数据从印度623个研究地点的诊所/医院病历中收集。纳入年龄在18 - 45岁的男女患者。提取人口统计学细节（年龄、性别、人体测量数据）、病史和家族史、久坐不动的生活方式、吸烟状况及饮酒数据。进行描述性和比较性分析（曼 - 惠特尼检验和卡方检验）。
在15006例诊断为高血压的年轻患者中（男性占63.6%），65.7%属于35 - 45岁年龄组。体重指数中位数为27.0kg/m²。仅诊断为高血压的患者占29.1%，而高血压的其他主要合并症为糖尿病（42.4%）和血脂异常（7.8%）。高血压合并糖尿病在35 - 45岁年龄组中最为普遍（43.8%）。超过一半的高血压患者（n = 7656）有久坐不动的生活方式。总体而言，分别有35.6%、47.3%和56.7%的患者饮酒、吸烟（现吸烟者和既往吸烟者）以及有高血压家族史。
结果显示，在年轻人群中，高血压在35 - 45岁年龄组中较为常见，糖尿病和血脂异常是常见的合并症。家族史、久坐不动的生活方式、吸烟、饮酒及体重指数也可能导致高血压。
