Wu Zhen-Yu, Han Hyun Ho, Kim Hee Jeong, Lee Jongwon, Chung Il Yong, Kim Jisun, Lee Saebyeol, Eom Jin Sup, Kim Sung-Bae, Gong Gyungyub, Kim Hak Hee, Son Byung-Ho, Ahn Sei-Hyun, Ko BeomSeok
Division of Breast Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul 05505, Republic of Korea.
Department of Breast Surgery, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, China.
Data Brief. 2021 Feb 5;35:106837. doi: 10.1016/j.dib.2021.106837. eCollection 2021 Apr.
Nipple-spring mastectomy (NSM) with immediate breast reconstruction is being increasingly used in the treatment of breast cancer [1]. However, there are limited available data on the prognostic implications of locoregional recurrence (LRR) following this surgical procedure. This article is a supplementary resource of the original research article by Wu ZY et al. entitled "Locoregional Recurrence Following Nipple-Sparing Mastectomy with Immediate Breast Reconstruction: Patterns and Prognostic Significance" [2] and presents data regarding the subsequent distant metastasis following the first LRR, as well as the prognoses for isolated local recurrences according to the site of recurrence after NSM and immediate breast reconstruction for primary breast cancer. Data from a total of 1,696 patients with primary breast cancer who underwent NSM with immediate reconstruction from March 2003 to December 2016 at the Asan Medical Center, Seoul, Korea, were retrospectively reviewed. An LRR as the first event was found to have developed in 172 patients. Among these, 117 cases (6.9%) involved isolated local recurrence, including 52 cases (3.1%) of nipple-areola complex recurrence, 41 cases (2.4%) of skin/subcutaneous recurrence, and 24 cases (1.4%) of chest wall recurrence. Kaplan-Meier survival analysis and the log-rank test were performed to compare the subgroups of local recurrence. In 172 patients with LRR, subsequent distant metastases were observed in 30 cases (17.4%). Our data may be helpful for conducting further in-depth investigations on salvage treatment options in patients with LRR following NSM and immediate breast reconstruction.
保乳乳晕切除术（NSM）联合即刻乳房重建术在乳腺癌治疗中的应用越来越广泛[1]。然而，关于该手术术后局部区域复发（LRR）的预后影响，可用数据有限。本文是吴ZY等人发表的原创研究文章《保乳乳晕切除术联合即刻乳房重建术后的局部区域复发：模式与预后意义》[2]的补充资源，呈现了首次LRR后随后发生远处转移的数据，以及根据NSM和原发性乳腺癌即刻乳房重建术后复发部位对孤立性局部复发患者的预后情况。回顾性分析了2003年3月至2016年12月在韩国首尔峨山医疗中心接受NSM联合即刻重建术的1696例原发性乳腺癌患者的数据。发现172例患者发生了首次LRR事件。其中，117例（6.9%）为孤立性局部复发，包括52例（3.1%）乳晕复合体复发、41例（2.4%）皮肤/皮下复发和24例（1.4%）胸壁复发。采用Kaplan-Meier生存分析和对数秩检验比较局部复发亚组。在172例发生LRR的患者中，观察到30例（17.4%）随后发生远处转移。我们的数据可能有助于对NSM联合即刻乳房重建术后LRR患者的挽救治疗方案进行进一步深入研究。
