Agashe Shruti, Hooper Destiny, Nisar Tariq, McCane David, Lee Jason, Chyuan Ling Ken, S Vahidy Farhaan, Chiu David, Gadhia Rajan R
Houston Methodist Neurological Institute, Houston Methodist Hospital, Houston, Texas, United States.
Epilepsy Behav Rep. 2021 Jan 7;15:100426. doi: 10.1016/j.ebr.2020.100426. eCollection 2021.
Mechanical thrombectomy 6-24 h after the last time where a patient was known to be without signs or symptoms of a stroke is the standard of care for patients with a stroke due to large vessel occlusion. This is referred to as thrombectomy within an extended time window. There have been very few studies looking at patients who had seizures within the first week (early post-stroke seizures) following mechanical thrombectomy in this extended time window. Our study suggests that this group of patients does not have a higher incidence of early post stroke seizures. Our findings do reveal however, that patients who do have early post-stroke seizures may have a less favorable functional outcome at 90 days than those who did not develop early seizures. Hence, rapid identification and subsequent treatment of seizures in these patients is important.
对于因大血管闭塞导致中风的患者，在已知患者最后一次无中风体征或症状后6至24小时进行机械取栓是治疗的标准。这被称为延长时间窗内的取栓。在这个延长时间窗内，很少有研究关注机械取栓后第一周内（中风后早期癫痫发作）发生癫痫的患者。我们的研究表明，这组患者中风后早期癫痫发作的发生率并不更高。然而，我们的研究结果确实显示，中风后早期癫痫发作的患者在90天时的功能预后可能比未发生早期癫痫发作的患者更差。因此，快速识别并随后治疗这些患者的癫痫发作很重要。
