From the Department of Medical Sciences, Surgery and Neurosciences, University of Siena (Dr. Pozza and Profs. Ferretti and Coluccia); University of Sydney, Faculty of Medicine and Health, Sydney Medical School, Nepean Clinical School, Discipline of Psychiatry (Prof. Starcevic); Emergency and Urgency Department, Azienda USL Toscana Sud Est (Dr. Pedani); Oncological Immunotherapy Unit (Dr. Crispino), Postoperative Intensive Care Unit (Dr. Governi), Interventional Radiology Unit (Dr. Luchi), and Cardiology Unit (Dr. Gallorini), Santa Maria alle Scotte University Hospital of Siena; SU/UCT MRC Unit on Anxiety and Stress Disorders, Department of Psychiatry, Stellenbosch University (Prof. Lochner).
Harv Rev Psychiatry. 2021;29(2):95-107. doi: 10.1097/HRP.0000000000000287.
After participating in this activity, learners should be better able to:• Assess the rates of co-occurring obsessive-compulsive personality disorder (OCPD) in patients with obsessive-compulsive disorder (OCD)• Identify characteristics related to OCD with co-occurring OCPD.
The current literature discloses discrepant findings regarding the rates of co-occurring obsessive-compulsive personality disorder (OCPD) in patients with obsessive-compulsive disorder (OCD). In addition, it is not clear which characteristics are related specifically to OCD with co-occurring OCPD. We conducted the first systematic review and meta-analysis of the studies of the prevalence of OCPD in patients with OCD. We also investigated potential moderators of the prevalence, including OCD severity, age of onset of OCD, sex, current age, methodological quality, and publication date of the studies. Electronic databases and gray literature were searched by two independent reviewers. A PRISMA systematic review with a random-effect meta-analysis was conducted. Thirty-four studies were included. A significant mean effect size of 0.25 without publication bias indicated that OCPD was present in 25% of patients with OCD, suggesting that the two conditions are distinct clinical entities. This prevalence was higher than the rates found in the literature for any other personality disorders among OCD patients. OCPD that occurs in the context of OCD was more likely to be present in males and to be characterized by a later age of onset of OCD, older age at assessment, and less severe OCD symptoms. Clinicians should consider these findings when assessing and planning treatment of OCD with co-occurring OCPD.
在参与此活动后，学习者应能够更好地：
评估强迫症 (OCD) 患者中同时存在强迫性人格障碍 (OCPD) 的比率
确定与 OCD 伴发的 OCPD 相关的特征。
目前的文献披露了强迫症 (OCD) 患者中同时存在强迫性人格障碍 (OCPD) 的比率存在差异的发现。此外，目前尚不清楚哪些特征与 OCD 伴发的 OCPD 具体相关。我们对 OCD 患者中 OCPD 患病率的研究进行了首次系统评价和荟萃分析。我们还研究了患病率的潜在调节因素，包括 OCD 严重程度、OCD 发病年龄、性别、当前年龄、方法学质量和研究发表日期。两名独立审查员通过电子数据库和灰色文献进行了搜索。进行了 PRISMA 系统评价和随机效应荟萃分析。共纳入 34 项研究。无发表偏倚的显著平均效应量为 0.25，表明 OCD 患者中有 25%存在 OCPD，表明这两种情况是不同的临床实体。这一患病率高于文献中 OCD 患者任何其他人格障碍的发生率。在 OCD 背景下发生的 OCPD 更可能发生在男性中，并且 OCD 的发病年龄较晚，评估时年龄较大，以及 OCD 症状较轻。临床医生在评估和计划 OCD 伴发 OCPD 的治疗时应考虑这些发现。
