Żerdziński Maciej, Burdzik Marcin, Dębski Paweł, Żmuda Roksana, Piegza Magdalena, Gorczyca Piotr
Psychiatric Department No 2, Dr. Krzysztof Czuma's Psychiatric Center, Katowice, Poland.
Department of Psychiatry and Sexology, Faculty of Medicine, Academy of Silesia, Katowice, Poland.
Front Psychiatry. 2025 Apr 24;16:1532966. doi: 10.3389/fpsyt.2025.1532966. eCollection 2025.
Obsessive-compulsive disorder (OCD) is characterized by obsessions and compulsions that significantly impair functioning. Obsessive-compulsive personality disorder (OCPD) co-occurs in 17-45% of OCD patients, worsening outcomes across multiple domains. Therefore, we aimed to study the impact of OCPD in more detail by analyzing selected comorbidities, emotional aspects, and sociodemographic data. This study assessed 78 OCD patients (average age 44.9 years, 34.61% OCPD), using Y-BOCS, BABS, BPAQ, BIS-11, YMRS, HDRS-17, and ASEX. Patients with comorbid OCPD had significantly worse outcomes in symptom severity (Y-BOCS = 0.0006), treatment duration (p = 0.0127), insight (BABS, p = 0.0185), aggression (p = 0.0266), impulsivity (p = 0.0469), depression (HDRS, p = 0.0178), mania (YMRS, p = 0.0003), and sexual dysfunction (ASEX, p = 0.008). OCPD was more prevalent in unemployed individuals (p = 0.046) and older patients (p = 0.009). No significant differences were found regarding gender, education, or relationship status. Obsessions and compulsions, such as contamination (p = 0.025), somatic (p = 0.018), ruminations (p = 0.003), and obsessional slowness (p = 0.007), were more common in the OCPD group. In the group with OCPD, aggression and OCD severity were correlated with increased levels of depression, which can be considered potential correlates of bipolarity in the relationship between OCD and OCPD. In conclusion, OCPD significantly worsens clinical outcomes in OCD across emotional, behavioral, and functional dimensions.
强迫症(OCD)的特征是强迫观念和强迫行为,这些会严重损害功能。强迫型人格障碍(OCPD)在17%至45%的强迫症患者中同时出现,会在多个领域使病情恶化。因此,我们旨在通过分析选定的共病情况、情感方面和社会人口统计学数据,更详细地研究OCPD的影响。本研究使用Y-BOCS、BABS、BPAQ、BIS-11、YMRS、HDRS-17和ASEX对78名强迫症患者(平均年龄44.9岁,34.61%患有OCPD)进行了评估。患有OCPD共病的患者在症状严重程度(Y-BOCS = 0.0006)、治疗持续时间(p = 0.0127)、洞察力(BABS,p = 0.0185)、攻击性(p = 0.0266)、冲动性(p = 0.0469)、抑郁(HDRS,p = 0.0178)、躁狂(YMRS,p = 0.0003)和性功能障碍(ASEX,p = 0.008)方面的结果明显更差。OCPD在失业个体(p = 0.046)和老年患者(p = 0.009)中更为普遍。在性别、教育程度或恋爱状况方面未发现显著差异。强迫观念和强迫行为,如污染(p = 0.025)、躯体方面(p = 0.018)、反复思考(p = 0.003)和强迫性迟缓(p = 0.007),在OCPD组中更为常见。在OCPD组中,攻击性和强迫症严重程度与抑郁水平升高相关,这可被视为强迫症与OCPD关系中双相性的潜在相关因素。总之,OCPD在情感、行为和功能维度上显著恶化了强迫症的临床结果。